Nicorelief (gum, lozenge)
Generic name: nicotine (gum, lozenge) [ NIK-oh-teen ]
Brand names: Leader Nicotine Polacrilex, Nicorelief, Nicorette, Thrive
Drug class: Smoking cessation agents
The Nicorelief brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is nicotine?
Nicotine is the primary ingredient in tobacco products.
Nicotine gum and lozenges are medical products used to aid in smoking cessation in adults. Using a controlled amount of nicotine helps reduce nicotine withdrawal symptoms when you quit smoking.
Nicotine may also be used for purposes not listed in this medication guide.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:
heart disease, irregular heartbeats;
a heart attack or stroke;
untreated or uncontrolled high blood pressure;
a seizure; or
if you are on a low salt diet.
Do not use this medicine if you are pregnant unless your doctor has told you to. Use effective birth control, and tell your doctor if you become pregnant during treatment.
Smoking cigarettes during pregnancy can cause low birth weight, miscarriage, or stillbirth. Using a nicotine replacement product during pregnancy or while breast-feeding may be safer than smoking. However, you should try to stop smoking without using a nicotine replacement product if you are pregnant or breast-feeding. Talk with your doctor about the best way for you to stop smoking.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
Nicotine lozenges may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).
Do not give this medicine to anyone under 18 years old without medical advice.
How should I take nicotine gum or lozenges?
This medicine is only part of a complete program of treatment that may also include counseling, group support, and behavior changes. Your success will depend on your participation in all aspects of your smoking cessation program.
Use exactly as directed on the label, or as prescribed by your doctor. Start using nicotine gum or lozenges on the same day you stop (quit) smoking or using tobacco products.
Your dose will depend on how many cigarettes you smoked daily before quitting. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
After removing the gum or lozenge, wrap it in paper and throw it away in a place where children and pets cannot reach it.
Do not use this medicine for longer than 12 weeks without the advice of your doctor.
Do not use more than one lozenge or piece of gum at a time. Do not use the gum and lozenges together at the same time.
Store at room temperature away from moisture, heat, and light.
Keep both used and unused gum and lozenges out of the reach of children or pets.
What happens if I miss a dose?
Since nicotine is used as needed, you are not likely to miss a dose. Do not use more than 20 lozenges or 24 pieces of gum per day.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. The amount of nicotine in a used or unused lozenge or piece of gum can be fatal to a child who accidentally sucks or chews on it. Seek emergency medical attention if this happens.
Overdose symptoms may include severe dizziness, nausea, vomiting, diarrhea, weakness, and fast heart rate.
What should I avoid while using nicotine gum or lozenges?
Do not eat or drink anything within 15 minutes before using the gum or lozenge or while the medicine is in your mouth.
Nicotine gum or lozenges side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:
fast or pounding heartbeats, fluttering in your chest;
blisters inside your mouth;
problems with your teeth or jaw; or
wheezing, tightness in your chest, trouble breathing.
Common side effects of Nicorelief may include:
dry mouth, upset stomach, burping, or hiccups;
mouth or throat soreness;
changes in taste; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect nicotine gum or lozenges?
Ask a doctor or pharmacist before using nicotine gum or lozenges with any other medications, especially:
asthma medication; or
any other smoking cessation medicine (bupropion, varenicline, Chantix, Zyban, Wellbutrin).
This list is not complete. Other drugs may affect nicotine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Generally, it takes 1 to 3 days after you stop using tobacco for nicotine to clear your blood system and up to 10 days for cotinine (the major breakdown product of nicotine) to be gone. This is an estimate because people process nicotine differently depending on their genetics and it also depends on how much you inhale and how much nicotine is in the cigarette. Continue reading
Nicotine withdrawal symptoms can last for several months, although they are typically at their worst during the first week of quitting, especially the first 3 to 5 days. Even though physical cravings tend to subside within a few weeks, the mental and emotional effects associated with nicotine withdrawal may last months, and you may need some help from your doctor to get through these, particularly if you have a history of anxiety or depression. Continue reading
More about Nicorelief (nicotine)
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- Drug class: smoking cessation agents
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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