Generic Name: testosterone nasal (tes TOS ter own NAY sul)
Brand Name: Natesto
What is Natesto?
Testosterone is a naturally occurring male hormone necessary for many processes in the body.
Natesto (for use in the nose) is used to treat conditions in men that result from a lack of natural testosterone.
Testosterone will not enhance athletic performance and should not be used for that purpose.
Natesto may also be used for purposes not listed in this medication guide.
Natesto should not be used by a woman. Testosterone can cause birth defects in an unborn baby.
Misuse of testosterone can cause dangerous or irreversible effects. Never use more than your prescribed dose. Do not share this medicine with another person.
Before taking this medicine
You should not use this medicine if you are allergic to Natesto gel, or if you have:
prostate cancer; or
male breast cancer.
To make sure Natesto is safe for you, tell your doctor if you have:
a history of problems with your sinuses or nasal passages;
a history of surgery on your nose or sinuses;
a broken nose (now or within the past 6 months);
a deviated septum (crooked nose);
breast cancer, prostate cancer;
enlarged prostate, urination problems;
sleep apnea (breathing stops during sleep);
heart disease, history of heart attack or stroke;
a history of blood clots; or
liver disease or kidney disease.
Older men who use Natesto may have an increased risk of prostate enlargement. If you are over 65, talk with your doctor about your specific risk.
This medicine should not be used by a woman. Testosterone can cause birth defects in an unborn baby. A pregnant woman should avoid coming into contact with Natesto gel. If contact does occur, wash with soap and water right away.
Natesto is not approved for use by anyone younger than 18 years old.
How should I use Natesto?
Follow all directions on your prescription label. Never use Natesto in larger amounts, or for longer than prescribed.
Misuse of testosterone can cause dangerous or irreversible effects, such as enlarged breasts, small testicles, infertility, high blood pressure, heart attack, stroke, liver disease, bone growth problems, addiction, and mental effects such as aggression and violence.
Do not share this medicine with another person.
Do not take by mouth or use on the skin. Natesto is for use only in the nose.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Blow your nose gently before using Natesto gel.
Wash with soap and water if the gel gets on your hands or skin while using it.
While using Natesto, you may need frequent blood tests.
Use Natesto regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
Do not share this medicine with another person.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using Natesto?
Avoid using other medications in your nose, unless your doctor tells you to.
Natesto side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using Natesto and call your doctor at once if you have:
increased urination (many times per day), loss of bladder control;
painful or difficult urination;
swelling, rapid weight gain, shortness of breath during sleep;
breast pain or swelling;
chest pain or pressure, pain spreading to your jaw or shoulder;
painful or bothersome erections;
nasal problems--runny or stuffy nose, sneezing, nosebleed, nose pain or dryness, scabs inside or around your nose;
signs of a blood clot in your leg--pain, swelling, warmth, or redness in one or both legs.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Natesto?
Tell your doctor about all your current medicines and any you start or stop using, especially:
This list is not complete. Other drugs may interact with testosterone nasal, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
More about Natesto (testosterone)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 3 Reviews – Add your own review/rating
- Drug class: androgens and anabolic steroids
Related treatment guides
Where can I get more information?
- Your pharmacist can provide more information about Natesto.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 1.02.
Date modified: March 06, 2018
Last reviewed: November 03, 2016