Medically reviewed on August 15, 2017
What is FIRST-Testosterone?
Testosterone is a naturally occurring male hormone necessary for many processes in the body.
FIRST-Testosterone (for the skin) is used to treat conditions in men that result from a lack of natural testosterone.
Testosterone will not enhance athletic performance and should not be used for that purpose.
FIRST-Testosterone may also be used for purposes not listed in this medication guide.
Testosterone can cause birth defects in an unborn baby. A pregnant woman should avoid coming into contact with this medicine, or with a man's skin where the medicine has been applied.
Topical testosterone is absorbed through the skin and can cause side effects or symptoms of male features in a child or woman who comes into contact with this medicine. Call your doctor if a person who has close contact with you develops enlarged genitals, premature pubic hair, increased libido, aggressive behavior, male-pattern baldness, excessive body hair growth, increased acne, irregular menstrual periods, or any signs of male characteristics.
Misuse of testosterone can cause dangerous or irreversible effects. Never use more than your prescribed dose. Do not share this medicine with another person.
Before taking this medicine
You should not use this medicine if you are allergic to testosterone patches or gels, or if you have;
prostate cancer; or
male breast cancer.
To make sure testosterone is safe for you, tell your doctor if you have ever had:
enlarged prostate, urination problems;
sleep apnea (breathing stops during sleep);
heart disease, heart attack, or stroke;
a blood clot;
liver disease or kidney disease.
Older men who use FIRST-Testosterone may have an increased risk of prostate enlargement or cancer. If you are over 65, talk with your doctor about your specific risk.
This medicine should not be used by a woman. Testosterone can cause birth defects in an unborn baby. A pregnant woman should avoid coming into contact with FIRST-Testosterone patches or gels, or with a man's skin areas where a patch has been worn or the gel has been applied. If contact does occur, wash with soap and water right away.
Do not use FIRST-Testosterone on anyone younger than 18 years old.
The testosterone transdermal patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test.
How should I use FIRST-Testosterone?
Follow all directions on your prescription label. Never use FIRST-Testosterone in larger amounts, or for longer than prescribed.
Misuse of testosterone can cause dangerous or irreversible effects, such as enlarged breasts, small testicles, infertility, high blood pressure, heart attack, stroke, liver disease, bone growth problems, addiction, and mental effects such as aggression and violence.
Do not share FIRST-Testosterone with another person.
Different brands of testosterone topical have different instructions for use. Not every brand of this medicine is used on the same skin areas. Some brands are applied to the shoulder, upper arm, or stomach. Other brands are applied to the thighs or to the underarms. Carefully follow the patient instructions provided with your medicine.
Do not apply FIRST-Testosterone to your penis or scrotum. Some brands of this medicine should also not be applied to the back, chest, or stomach areas. Apply this medicine only to the skin areas recommended for your specific brand of testosterone topical.
Apply testosterone gel to dry skin after showering or bathing. Allow the medicine to dry for at least 5 minutes before you dress.
Wash your hands with soap and water after applying the gel.
Cover treated skin areas with clothing to keep from getting this medicine on other people. If someone else does come into contact with a treated skin area, they must wash the contact area right away with soap and water.
Apply the transdermal skin patch to a flat, clean, dry, and undamaged area of skin on your back, stomach, upper arm, or thigh. Wear the patch for 24 hours and then replace it with a new patch. Choose a different skin area each time you put on a new patch. Do not use the same skin area twice in a 7-day period.
While using FIRST-Testosterone, you may need frequent blood tests.
Use FIRST-Testosterone regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
Store at room temperature away from moisture and heat.
Keep each skin patch in the foil pouch until you are ready to use it. Do not use a skin patch that has been cut or damaged After removing a skin patch, fold it closed with the sticky side in, and throw it away in a place where pets and children cannot reach it.
What happens if I miss a dose?
Apply the gel or skin patch as soon as you remember. Skip the missed dose if it is almost time to apply your next dose. Do not use extra patches or gel to make up the missed dose.
If a skin patch falls off in the morning, reapply it. If it does not stick well, apply a new patch. If the patch falls off in the afternoon and cannot be reapplied, wait until your regular patch replacement time in the evening before putting on a new patch.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using FIRST-Testosterone?
Do not apply FIRST-Testosterone to your penis or your scrotum.
Avoid swimming, bathing, or showering for 2 to 5 hours after applying testosterone gel. Follow the directions provided with your specific brand.
Avoid using lotions, oils, or other skin products on the area where you will apply the skin patch. The patch may not stick properly to the skin.
Testosterone gel may be flammable. Avoid using near open flame, and do not smoke until the gel has completely dried on your skin.
If your doctor recommends a topical steroid medicine such as hydrocortisone to treat skin irritation caused by wearing a testosterone skin patch, avoid using an ointment form of the steroid.
FIRST-Testosterone side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using FIRST-Testosterone and call your doctor at once if you have:
increased urination (many times per day), loss of bladder control;
painful or difficult urination;
breast pain or swelling;
painful or bothersome erections;
swelling, rapid weight gain, shortness of breath during sleep;
chest pain or pressure, pain spreading to your jaw or shoulder;
signs of a blood clot in the lung--chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or
signs of a blood clot in your leg--pain, swelling, warmth, or redness in one or both legs.
Topical testosterone is absorbed through the skin and can cause symptoms of male features in a woman or child who comes into contact with the medication. Call your doctor if your female partner has male-pattern baldness, excessive body hair growth, increased acne, irregular menstrual periods, or any other signs of male characteristics.
Common side effects may include:
redness, itching, burning, hardened skin or other irritation where the medicine was applied or where the skin patch was worn;
headache, mood changes;
increased red blood cells (may cause dizziness, itching, redness in your face, or muscle pain);
frequent or prolonged erections; or
high blood pressure--severe headache, blurred vision, pounding in your neck or ears.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect FIRST-Testosterone?
Tell your doctor about all your current medicines and any you start or stop using, especially:
This list is not complete. Other drugs may interact with testosterone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 14.01.
More about FIRST-Testosterone (testosterone)
- FIRST-Testosterone Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- En Español
- Drug class: androgens and anabolic steroids