Generic name: montelukast (mon te LOO kast)
Brand name: Singulair
Dosage forms: oral granule (4 mg); oral tablet (10 mg); oral tablet, chewable (4 mg; 5 mg)
Drug class: Leukotriene modifiers
What is montelukast?
Montelukast is a leukotriene (loo-koe-TRY-een) inhibitor that is used to prevent asthma attacks in adults and children at least 2 years old. Montelukast is also used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs) in adults and children who are at least 6 years old.
Montelukast is also used to treat symptoms of seasonal or year-round (perennial) allergies in adults and children at least 2 years old, after other treatments did not work.
If you already take montelukast to prevent asthma or allergy symptoms, do not use an extra dose to treat exercise-induced bronchoconstriction.
Montelukast may also be used for purposes not listed in this medication guide.
Stop taking montelukast and call your doctor right away if you have any unusual changes in mood or behavior (such as agitation, confusion, depression, sleep problems, compulsive behaviors, hallucinations, or suicidal thoughts or actions).
Before taking this medicine
You should not use montelukast if you are allergic to it.
Tell your doctor if you have ever had:
mental illness or psychosis; or
asthma, or a history of severe allergic reaction (sneezing, runny or stuffy nose, wheezing, shortness of breath) after taking aspirin or another NSAID.
The chewable tablet may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).
Tell your doctor if you are pregnant or breastfeeding.
Do not give this medicine to a child without a doctor's advice.
How should I take montelukast?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Montelukast is not a fast-acting rescue medicine for asthma attacks. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working.
Montelukast is usually taken once every evening, with or without food.
For exercise-induced bronchoconstriction, take a single dose at least 2 hours before exercise, and do not take another dose for at least 24 hours.
Swallow the regular tablet whole, with a glass of water.
You must chew the chewable tablet before you swallow it.
Place the oral granules directly in your mouth and swallow, or mix them with applesauce, mashed carrots, rice, or ice cream. The granules may also be mixed with baby formula or breast milk. Do not use any other type of liquid. Use the mixture within 15 minutes. Do not save for later use.
If you also use an oral steroid medication, you should not stop using it suddenly. Follow your doctor's instructions about tapering your dose.
Do not change your dose or stop using asthma medication without your doctor's advice.
Store at room temperature away from moisture and heat. Do not open a packet of oral granules until you are ready to use the medicine.
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking montelukast?
Avoid situations or activities that may trigger an asthma attack.
If your asthma symptoms get worse when you take aspirin, avoid taking aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
Montelukast side effects
Get emergency medical help if you have signs of an allergic reaction: hives, blisters, severe itching; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your doctor right away if you have signs of blood vessel inflammation: flu-like symptoms, severe sinus pain, a skin rash, numbness or a "pins and needles" feeling in your arms or legs.
Some people using montelukast have had new or worsening mental problems. Stop taking montelukast and call your doctor right away if you have unusual changes in mood or behavior, such as:
agitation, aggression, feeling restless or irritable;
anxiety, depression, confusion, problems with memory or attention;
stuttering, tremors, uncontrolled muscle movements;
suicidal thoughts or actions;
hallucinations, sleep problems, vivid, dreams, sleep-walking; or
compulsive or repetitive behaviors.
Common side effects may include:
stomach pain, diarrhea;
fever or other flu symptoms;
ear pain or full feeling, trouble hearing;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect montelukast?
More about montelukast
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 477 Reviews
- Drug class: leukotriene modifiers
- Other brands
Related treatment guides
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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