Skip to Content

Jay-Phyl

Generic Name: dyphylline and guaifenesin (DYE fil een and gwye FEN e sin)
Brand Name: Difil-G Forte, Jay-Phyl

Medically reviewed on January 9, 2018

What is Jay-Phyl?

Dyphylline is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Jay-Phyl is a combination medicine used to treat cough and breathing problems caused by conditions such as bronchial asthma, chronic bronchitis, or emphysema.

This medication is not a rescue medication for asthma or bronchitis, and is not a cure for emphysema.

Jay-Phyl may also be used for purposes not listed in this medication guide.

Important Information

Jay-Phyl should not be given to a child younger than 6 years old.

Before taking this medicine

You should not use Jay-Phyl if you are allergic to dyphylline or guaifenesin. This medication will not treat an asthma attack.

To make sure Jay-Phyl is safe for you, tell your doctor if you have:

FDA pregnancy category C. It is not known whether Jay-Phyl will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Dyphylline and guaifenesin can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Jay-Phyl should not be given to a child younger than 6 years old.

How should I take Jay-Phyl?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Take Jay-Phyl with food if it upsets your stomach.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include agitation, vomiting, extreme thirst, ringing in your ears, sweating, feeling hot, slow or irregular heart rate, or seizure (convulsions).

What should I avoid while taking Jay-Phyl?

Ask a doctor or pharmacist before using any cough or cold medicine. Guaifenesin is contained in many combination medicines. Taking certain products together can cause you to get too much guaifenesin.

Jay-Phyl side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pounding heartbeats or fluttering in your chest;

  • rapid breathing, feeling short of breath;

  • seizure (convulsions); or

  • coughing up blood or vomit that looks like coffee grounds.

Common side effects may include:

  • nausea, vomiting, stomach pain, diarrhea;

  • headache;

  • feeling restless or irritable;

  • sleep problems (insomnia); or

  • flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Jay-Phyl?

Other drugs may interact with dyphylline and guaifenesin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

More about Jay-Phyl (dyphylline / guaifenesin)

Consumer resources

Other brands: Difil-G Forte

Professional resources

Related treatment guides

Hide