Skip to main content

Jay-Phyl Side Effects

Generic name: dyphylline / guaifenesin

Medically reviewed by Last updated on Apr 29, 2024.

Note: This document contains side effect information about dyphylline / guaifenesin. Some dosage forms listed on this page may not apply to the brand name Jay-Phyl.

Applies to dyphylline / guaifenesin: oral tablet.


Dyphylline and guaifenesin should not be given to a child younger than 6 years old.

Get emergency medical help if you have any of these signs of an allergic reaction while taking dyphylline / guaifenesin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to dyphylline / guaifenesin: oral capsule, oral liquid, oral syrup, oral tablet.


Frequency not reported: Cardiac palpitation[Ref]

Nervous system

Frequency not reported: Headache, CNS stimulation[Ref]


Frequency not reported: Nausea[Ref]

More about Jay-Phyl (dyphylline / guaifenesin)

Patient resources

Other brands

Difil G, Difil-G Forte

Related treatment guides


1. (2004) "Product Information. Difil G (dyphylline-guaifenesin)." SJ Pharmaceuticals LLC

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.