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Dyphylline / guaifenesin Pregnancy and Breastfeeding Warnings

Medically reviewed by Last updated on Dec 30, 2022.

Dyphylline / guaifenesin is also known as: D-G, Difil G, Difil-G Forte, Dilex-G, Dilex-G 200, Dilex-G 400, Dilor-G, Dy-G, Dyfilin GG, Dyflex-G, Dyline GG, Dyphyl GG, Dyphyllin-GG, Dyphylline GG, Dyphylline GG ES, Jay-Phyl, LGG, Lufyllin-GG, Panfil G

Dyphylline / guaifenesin Pregnancy Warnings

Animal studies have not been conducted. There are no controlled data in human pregnancy. It is unknown if this drug can cause fetal harm or affect reproduction capacity.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

This drug should be used during pregnancy only if clearly needed.

US FDA pregnancy category: C

See references

Dyphylline / guaifenesin Breastfeeding Warnings

Caution is recommended.

Excreted into human milk: Yes

-Dyphylline is present in human milk at about twice the maternal plasma concentration.

See references

References for pregnancy information

  1. "Product Information. Difil G (dyphylline-guaifenesin)." SJ Pharmaceuticals LLC (2004):

References for breastfeeding information

  1. "Product Information. Difil G (dyphylline-guaifenesin)." SJ Pharmaceuticals LLC (2004):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.