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Atropine (injection)

Generic Name: atropine (injection) (AT roe peen)
Brand Name: AtroPen, Sal-Tropine, Atreza, AtroPen Auto-Injector
Dosage Forms: injectable solution (0.05 mg/mL; 0.1 mg/mL; 0.4 mg/mL; 0.4 mg/mL-NaCl 0.9%; 1 mg/mL); intramuscular solution (2 mg/0.7 mL); intravenous solution (0.1 mg/mL; 0.4 mg/mL-NaCl 0.9%)

Medically reviewed by on March 12, 2021. Written by Cerner Multum.

What is atropine?

Atropine is used to help reduce saliva, mucus, or other secretions in your airway during a surgery. Atropine is also used to treat spasms in the stomach, intestines, bladder, or other organs.

Atropine is sometimes used as an antidote to treat certain types of poisoning.

Atropine may also be used for purposes not listed in this medication guide.


Before you receive atropine, tell your doctor about all your medical conditions or allergies, and all the medicines you are using. Also make sure your doctor knows if you are pregnant or breast-feeding.

Before taking this medicine

Tell your doctor if you have ever had:

In an emergency, you may not be able to tell caregivers if you are pregnant or breastfeeding. Make sure any doctor caring for your pregnancy or your baby knows you received atropine.

How is atropine given?

Atropine is injected into a muscle, under the skin, or as an infusion into a vein. A healthcare provider will give you this injection.

What happens if I miss a dose?

Because you will receive atropine in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

Since atropine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving atropine?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Atropine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • a light-headed feeling, like you might pass out;

  • pounding heartbeats or fluttering in your chest;

  • nausea, vomiting, stomach pain, feeling full after eating a small amount;

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;

  • trouble swallowing;

  • feeling restless or excited;

  • tremors, problems with balance or muscle movement;

  • increased thirst, hot and dry skin;

  • tiredness; or

  • a severe skin rash.

Common side effects may include:

  • fast heartbeats;

  • dry mouth, nose, or throat;

  • dry eyes, blurred vision, your eyes may be more sensitive to light;

  • dizziness; or

  • headache, drowsiness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect atropine?

Atropine can make it harder for your body to absorb other medicines you take by mouth. Tell your doctor about all your other medicines, especially mexiletine.

Other drugs may affect atropine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.