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Digex NF

Generic Name: hyoscyamine and phenyltoloxamine (HYE oh SYE a meen and FEEN il toe LOX a meen)
Brand Name: Digex NF

Medically reviewed on Dec 4, 2017

What is Digex NF?

Digex NF produces many effects in the body, including relief from muscle spasms in the stomach and intestines. This medicine also reduces the fluid secretions of many organs and glands in the body, such as the stomach.

Phenyltoloxamine is an antihistamine that reduces the effects of natural chemical histamine in the body.

The combination of hyoscyamine and phenyltoloxamine is used to treat indigestion (upset stomach, gas, bloating), and to reduce stomach acid.

Digex NF may also be used for purposes not listed in this medication guide.

Important Information

You should not take Digex NF if you are allergic to it, or if you have kidney disease, a bladder or intestinal obstruction, severe ulcerative colitis, toxic megacolon, glaucoma, myasthenia gravis, problems with your esophagus, or if you are unable to urinate.

Do not use Digex NF if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, heart disease, high blood pressure, coronary artery disease, or a thyroid disorder.

Before you take Digex NF, tell your doctor if you have a heart rhythm disorder, liver or kidney disease, low blood pressure, a brain injury or seizure disorder, enlarged prostate, urination problems, if you have been sick with diarrhea or fever, or if you take medicine that contains potassium.

Digex NF works best if you take it before a meal.

Avoid taking an antacid at the same time you take Digex NF. Antacids can make it harder for your body to absorb this medicine. If you use an antacid, take it after you have taken this medicine and eaten a meal.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol can increase certain side effects of hyoscyamine and phenyltoloxamine.

Before taking this medicine

You should not take Digex NF if you are allergic to it, or if you have kidney disease, a bladder or intestinal obstruction, severe ulcerative colitis, toxic megacolon, glaucoma, myasthenia gravis, problems with your esophagus, or if you are unable to urinate.

Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, heart disease, high blood pressure, coronary artery disease, or a thyroid disorder.

To make sure you can safely take Digex NF, tell your doctor if you have any of these other conditions:

  • a heart rhythm disorder;

  • liver or kidney disease;

  • low blood pressure;

  • a brain injury or seizure disorder;

  • enlarged prostate or urination problems;

  • if you have been sick with diarrhea or fever; or

  • if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

FDA pregnancy category C. It is not known whether Digex NF will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Hyoscyamine and phenyltoloxamine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from this medicine.

How should I take Digex NF?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Digex NF works best if you take it before a meal.

If you break or open a Digex NF capsule, avoid inhaling the powder medicine inside the capsule.

Pay special attention to your dental hygiene. This medication can cause dry mouth leading to tooth decay.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take your dose as soon as you remember, but only if you are getting ready to eat a meal. Do not take extra medicine to make up the missed dose.

If you skip a meal, do not take your dose of Digex NF. Wait until your next meal.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include confusion, severe dizziness, extreme thirst, fever, hot and dry skin, vision problems, trouble swallowing, or seizure (convulsions).

What should I avoid while taking Digex NF?

Avoid taking an antacid at the same time you take Digex NF. Antacids can make it harder for your body to absorb this medicine. If you use an antacid, take it after you have taken this medicine and eaten a meal.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Drinking alcohol can increase certain side effects of hyoscyamine and phenyltoloxamine.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Digex NF can decrease sweating and you may be more prone to heat stroke.

Digex NF side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Digex NF and call your doctor at once if you have a serious side effect such as:

  • fast or uneven heart rate;

  • severe stomach cramps or constipation;

  • confusion, agitation, behavior changes, hallucinations, feelings of extreme happiness;

  • loss of balance or coordination, problems with speech;

  • double vision; or

  • ongoing diarrhea or vomiting.

Less serious side effects may include:

  • headache, dizziness, drowsiness, memory problems;

  • dry mouth;

  • nausea;

  • mild constipation;

  • decreased sweating;

  • sleep problems (insomnia);

  • feeling restless or excited (especially in children); or

  • impotence, loss of interest in sex, or trouble having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Digex NF?

Before using Digex NF, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by this medicine.

Tell your doctor about all other medicines you use, especially:

This list is not complete and other drugs may interact with Digex NF. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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