When should you take ezetimibe?
Can I take ezetimibe at the same time as statins or other cholesterol medications?
There is no specific time of the day that is best to take ezetimibe, as it works exactly the same whether you take in the morning, afternoon or at night.
- Ezetimibe is taken once a day, at the same time each day and it can be taken with or without food.
- When choosing a time to take your ezetimibe it is important to pick a time that is most convenient for you and when you are most likely to remember to take it.
- If you are taking other medications consider whether your other medication can be taken at the same time as ezetimibe or whether they need to be taken at a different time.
Can I take ezetimibe at the same time as my other cholesterol medications?
Ezetimibe is sometimes prescribed with other cholesterol lowering medications.
These cholesterol lowering medications can be taken at the same time as ezetimibe:
- atorvastatin
- fenofibrate
- fluvastatin
- lovastatin
- pravastatin
- simvastatin
You should not take ezetimibe together with a statin medicine if you have active liver disease or if you are pregnant or breastfeeding a baby.
These cholesterol lowering medications need to be taken at a different time time to ezetimibe:
- cholestyramine
- colesevelam
- colestipol
If you have taken ezetimibe you need to wait 2 hours before taking cholestyramine, colestipol, or colesevelam.
If you have taken cholestyramine, colestipol, or colesevelam you need to wait at least 4 hours before taking ezetimibe.
Bottom line:
- Ezetimibe can be taken any time of the day, with or without food.
- Ezetimibe should be taken consistently at the same time each day.
- Take it at a time of the day when you are most likely to remember to take it.
References
Ezetimibe Medication Information: https://www.drugs.com/ezetimibe.html
Read next
Does Zetia (ezetimibe) cause memory loss?
Memory loss is not a side effect of Zetia (ezetimibe) when it is used alone to treat high cholesterol. Zetia is often used with diet and other cholesterol lowering medications like statins which have been linked with cognitive impairment (memory loss, forgetfulness, or confusion). Continue reading
Can Zetia (ezetimibe) cause liver damage?
Yes, Zetia (ezetimibe) can cause liver damage, although it is very rare. Monitor liver enzymes for the development of serious toxic hepatitis and consider ezetimibe discontinuation if it develops. Perform liver tests during ezetimibe initiation and regularly thereafter and consider withdrawal of ezetimibe and/or the statin (if coadministered) should an increase in ALT or AST ≥3 X upper limit of normal (ULN) persist. Continue reading
How does Zetia (ezetimibe) work to lower cholesterol?
It reduces cholesterol absorption from the small intestine so there is less cholesterol delivered to the liver. This means there is a lower amount of cholesterol stored in the liver, which leads to more cholesterol being cleared from the blood. Continue reading
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Drug information
- Ezetimibe Information for Consumers
- Ezetimibe prescribing info & package insert (for Health Professionals)
- Side Effects of Ezetimibe (detailed)
- Ezetimibe user reviews (176)
Related support groups
- Ezetimibe (17 questions, 15 members)
- High Cholesterol (102 questions, 269 members)