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When should you take ezetimibe?

Medically reviewed by Melisa Puckey, BPharm. Last updated on July 29, 2025.

Official Answer by Drugs.com

Can I take ezetimibe at the same time as statins or other cholesterol medications?

Ezetimibe should be taken consistently at the same time each day, at a time of the day when you are most likely to remember to take it. Ezetimibe is usually taken once a day.

Can I take ezetimibe at the same time as my other cholesterol medications?

Ezetimibe is sometimes prescribed with other cholesterol-lowering medications.

Cholesterol-lowering medications that can be taken at the same time as ezetimibe*:

*If you have active liver disease, or if you are pregnant or breastfeeding a baby, then you should not take ezetimibe together with the above statin medicines.

Cholesterol-lowering medications that need to be taken at a different time from ezetimibe:

If you have taken ezetimibe, you need to wait 2 hours before taking cholestyramine, colestipol, or colesevelam.
If you have taken cholestyramine, colestipol, or colesevelam, you need to wait at least 4 hours before taking ezetimibe.

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References

Ezetimibe Medication Information: https://www.drugs.com/ezetimibe.html

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