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What type of Hepatitis C is Zepatier used to treat?

Medically reviewed by Judith Stewart, BPharm. Last updated on Feb 23, 2022.

Official answer


Zepatier (elbasvir and grazoprevir) is used to treat chronic hepatitis C (HCV) genotype 1 or 4 infection in adults and children 12 years of age and older or weighing at least 66 pounds (30 kilograms).

Zepatier is given with or without ribavirin for HCV in patients with genotype 1 (the most common, 70% of HCV patients) or 4 (the least common, ~1% of HCV patients).

Zepatier is used only if your HCV has these specific genetic markers, for which your doctor will test.

In clinical trials, cure rates at 12 weeks ranged from 94 to 97 percent in genotype 1 and from 97 to 100 percent in genotype 4-infected subjects.

Zepatier tablets are taken once daily with or without food.

The most common side effects of Zepatier without ribavirin include fatigue, headache and nausea.
The most common side effects of Zepatier with ribavirin include anemia and headache.

See What are the new drugs for the treatment of hepatitis C?

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