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What type of Hepatitis C is Zepatier used to treat?

Medically reviewed by Last updated on Apr 27, 2020.

Official Answer


Zepatier is used to treat chronic hepatitis C genotype 1 or 4 infection in adults.

Zepatier (elbasvir and grazoprevir) is a once-daily oral agent FDA-approved for HCV in February 2016.

Zepatier is given with or without ribavirin for HCV in adults with genotypes 1 (the most common, 70% of HCV patients) or 4 (the least common, ~1% of HCV patients).

Zepatier is used only if your HCV has these specific genetic markers, for which your doctor will test. In clinical trials, cure rates at 12 weeks ranged from 94 to 97 percent in genotype 1 and from 97 to 100 percent in genotype 4-infected subjects.

Common side effects with Zepatier include headache, nausea, and fatigue.

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