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Can you take Xanax if you are on prednisone?

Medically reviewed by Drugs.com. Last updated on Oct 23, 2024.

Official answer

by Drugs.com

Yes, Xanax and prednisone can be taken together. There is only a minor interaction between the two. Minor interactions do not usually cause harm OR require a change in therapy. Your health care provider will determine if adjustments to your medication are needed.

Certain corticosteroids may decrease the plasma concentration of some benzodiazepines. The mechanism is related to induction of hepatic cytochrome P450 enzymes responsible for benzodiazepine metabolism. The clinical significance may depend on the dosage and duration of corticosteroid therapy and be of greater importance with oral administration of benzodiazepines.

Xanax and Prednisone Interactions Report

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What is considered a high dose of prednisone?

The starting dose of prednisone may be between 5 mg to 60 mg per day. A dose above 40 mg per day may be considered a high dose. However, everybody responds differently to prednisone, so what might be a high dose depends on the person and the condition. Continue reading

What's a good prednisone taper schedule?

The best prednisone taper will depend upon how long you have been taking the medicine, your dose, and why you are being treated. If you've been treated with a high dose of prednisone, or taken it for more than a few weeks, you will need to slowly stop your medicine, usually over a period of days, weeks or months. Your healthcare provider will determine your prednisone tapering schedule. Continue reading

Is it OK to drink alcohol with Prednisone?

Although there is no direct drug interaction between prednisone and alcohol, mixing them together is not a good idea because some of the effects of alcohol and the side effects of prednisone are similar, so taking both at the same time can increase the risk of these side effects occurring. Continue reading

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