Who makes Skyrizi and where is it made?
Skyrizi is made by AbbVie Inc., a U.S. pharmaceutical company located in North Chicago, Illinois. They have multiple manufacturing plants, including ones in North Chicago, IL, Lake County, IL, Worcester, MA and Wyandotte, MI., as well as globally. You can contact AbbVie at 1-800-222-6885 or online at Abbvie.com.
When was Skyrizi approved?
In April 2019 the U.S. Food and Drug Administration (FDA) first approved Skyrizi (risankizumab-rzaa) for the treatment of plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.
Skyrizi is also approved for adults to treat active psoriatic arthritis and Crohn's disease (both approved in 2022), and ulcerative colitis (approved in 2024).
Skyrizi is classified as an interleukin-23 (IL-23) inhibitor and helps to lower inflammation and improve symptoms in these autoimmune disorders.
What are Skyrizi's most common side effects?
Common side effects in plaque psoriasis and psoriatic arthritis include:
- upper respiratory infections
- headache
- fatigue
- injection site reactions
- tinea (fungal) infections.
In Crohn's disease, common side effects include upper respiratory infections, headache, and arthralgia (joint pain) during the induction period, and arthralgia, injection site reactions, abdominal pain, anemia (low red blood cells), pyrexia (fever), back pain, arthropathy (joint disease), and urinary tract infection during long-term, maintenance treatment.
In ulcerative colitis, side effects include arthralgia (joint pain) during the induction period and arthralgia, pyrexia (fever), injection site reactions, and rash during the maintenance phase of treatment.
Learn More: Skyrizi Uses and Safety Information
This is not all the information you need to know about Skyrizi (risankizumab-rzaa) for safe and effective use and does not take the place of your healthcare provider's directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.
Related questions
- What does psoriasis look like?
- How do you get psoriasis and is it contagious?
- How does Tremfya work?
References
- Skyrizi (risankizumab-rzaa) prescribing information. AbbVie Inc. 6/2022. Accessed June 20, 2022 at https://www.rxabbvie.com/pdf/skyrizi_pi.pdf
- AbbVie. At a glance. Accessed June 19, 2024 at https://www.abbvie.pr/our-company/at-a-glance.html
Read next
How does Ilumya work to treat psoriasis?
Ilumya works by binding selectively to interleukin-23 (IL-23) which is a naturally occurring cytokine. IL-23 plays a key role in promoting inflammation and regulating other cytokines (such as IL-17) and inflammatory substances, such as TNF-α3-7. By blocking the effects of IL-23, Ilumya helps control the release of IL-17 and TNF-α, which reduces inflammation associated with psoriasis. It also decreases how many inflammatory cells are present within psoriatic lesions, helps prevent plaque formation, and resolves tissue damage. Continue reading
What's a good prednisone taper schedule?
The best prednisone taper will depend upon how long you have been taking the medicine, your dose, and why you are being treated. If you've been treated with a high dose of prednisone, or taken it for more than a few weeks, you will need to slowly stop your medicine, usually over a period of days, weeks or months. Your healthcare provider will determine your prednisone tapering schedule. Continue reading
Prednisone: What are 12 Things You Should Know?
Prednisone has been on the market for more than 70 years but is still one of the most commonly prescribed anti-inflammatory or immunosuppressive medications. Prednisone is used to treat dozens of different conditions such as skin disorders, breathing disorders, allergies, arthritis, and ulcerative colitis. But did you know it also has some pretty serious side effects as well?
Continue readingSee also:
Related medical questions
- Where should you not use triamcinolone acetonide cream?
- What are the new drugs for plaque psoriasis?
- Why should I take folic acid with methotrexate?
- Is triamcinolone acetonide an antifungal cream?
- How do you use clobetasol propionate on your scalp?
- Clobetasol vs. triamcinolone - how do they compare?
- What is a substitute for fluocinonide cream?
- Sotyktu vs Otezla: How do they compare?
- How long does methotrexate stay in your system?
- Halobetasol vs. clobetasol - How do they compare?
- Does taking vitamin D help with psoriasis?
- Can clobetasol be used for toenail fungus?
- How long does it take for Skyrizi to work?
- What are 6 key Taltz side effects to watch out for?
- What causes Plaque Psoriasis?
- How does Taltz compare to Cosentyx for psoriatic arthritis?
- How long does clobetasol stay in your system?
- What's the dosing schedule for Skyrizi?
- Does Feverfew interact with any drugs?
- Is fluocinonide an antifungal cream?
- How long does it take for Otezla to work?
- How long should you use fluocinonide for?
- How do you inject Humira?
- Cosentyx vs Humira: How do they compare?
Drug information
Related support groups
- Psoriasis (109 questions, 310 members)
- Skyrizi (17 questions, 9 members)
- Risankizumab (8 questions, 3 members)
- Crohn's Disease (62 questions, 286 members)
- Plaque Psoriasis (94 questions, 69 members)
- Psoriatic Arthritis (91 questions, 282 members)