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How long should you take Repatha?

Medically reviewed by Melisa Puckey, BPharm. Last updated on Sep 19, 2024.

Official Answer by Drugs.com

Why do you need to take Repatha (evolocumab) long term?

Repatha is a medicine that is designed to be taken long term to reduce the risk of cardiovascular disease. Repatha works while you are using Repatha so if you stop taking it, and once all of the medicine has has left your body, then it will stop having its beneficial effect. It is NOT the type of medicine that can fix a health issue after a short treatment course.

What does Repatha do? and why do you need to take it for a long time?

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Who takes Repatha?

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What is the difference between Leqvio and Repatha?

Leqvio and Repatha are both injectable medicines that are used for the treatment of high cholesterol, by specifically lowering low density lipoprotein (LDL) levels. Although they both inhibit PCSK9 they work by different mechanisms. Repatha is a monoclonal antibody that binds directly to PCSK9 in the liver preventing it from binding to LDL receptors. Leqvio blocks the PCSK9 protein by interfering with the translation of PCSK9 messenger RNA. Both have the same result – and that is freeing up LDL receptors on the surface of liver cells which allows LDL cholesterol to be removed from the blood.

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What is the best time of day to take Repatha?

You can inject Repatha at any time of the day, but usually people prefer injecting Repatha during daylight hours because it takes 30 to 45 minutes for it to warm up to room temperature, and you need to be able to easily see what you are doing while you are injecting it. Continue reading

How long can Repatha be kept unrefrigerated?

Repatha can be left unrefrigerated for up to 30 days at room temperature between 68°F to 77°F (20°C to 25°C) as long as it is kept in its original box and is not kept somewhere that gets hotter than 77°F (25°C), for example, a car glove box. This makes it easier to take your medicine with you when you’re on the go. Do not put Repatha back in the refrigerator once you have taken it out. Continue reading

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