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Can Leronlimab (PRO 140) be used to treat COVID-19 (coronavirus)?

Medically reviewed by Melisa Puckey, BPharm. Last updated on March 19, 2025.

Official Answer by Drugs.com

Can Leronlimab (PRO 140) be used to treat COVID-19 (coronavirus)

What is Leronlimab?

Humanized IgG4 monoclonal antibody (mAb)

Belongs to a group of medicine that are CCR5 antagonists.

How does Leronlimab work on COVID-19?

Related questions

Is Leronlimab an approved medicine by the FDA?

What other conditions is Leronlimab use for?

What happens next?

We need to wait for the trials to be completed to find out how well leronlimab works to decrease any breathing and lung issues in COVID-19 and whether it speeds up patients recovery.

The studies will also be looking for any side effects or any unexpected issues that may reduce leronlimab usefulness in COVID-19 patients

Bottom line

Related Drug Information

References
  1. https://clinicaltrials.gov/ct2/show/study/NCT03902522
  2. https://www.cytodyn.com/newsroom/press-releases/detail/400/cytodyn-files-fda-suggested-modifications-to-ind-and
  3. https://www.cytodyn.com/newsroom/press-releases/detail/399/leronlimab-used-in-seven-patients-with-severe-covid-19
  4. https://aidsinfo.nih.gov/drugs/423/leronlimab/0/professional
  5. https://www.frontiersin.org/articles/10.3389/fimmu.2017.01981/full

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