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Is Tylenol (acetaminophen) a blood thinner?

Medically reviewed by Last updated on Oct 12, 2023.

Official answer


No, Tylenol (acetaminophen) is not classified as a blood thinner-type of drug, but Aspirin (acetylsalicylic acid) is a blood thinner.

Acetaminophen is considered the pain and fever reliever of choice for most patients receiving oral anticoagulant therapy like warfarin. However, if you are taking a high dose of acetaminophen over the long-term, caution is recommended during combined therapy with warfarin, particularly if high doses of acetaminophen are used for a prolonged period.

If you take warfarin, tell your doctor that you take acetaminophen and contact them if you experience any signs of bleeding like nosebleeds, bruising, headache, dizziness, weakness, pain, prolonged bleeding from cuts or gums after brushing, heavy menstrual flow, unexpected vaginal bleeding, red or dark urine, or red or black (tarry) stools.

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