Is Tylenol (acetaminophen) an anti-inflammatory drug?
Medically reviewed by Drugs.com. Last updated on April 4, 2025.
No, Tylenol (acetaminophen) is not an anti-inflammatory. Tylenol is classified as a painkiller for mild to moderate pain and fever. There is a theory that acetaminophen may inhibit COX enzymes, similar to the way NSAIDs work, but without the anti-inflammatory effect. Tylenol typically has a lower effect on pain due to inflammation than NSAIDs.
Acetaminophen is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.
Acetaminophen is usually the pain reliever of choice for patients who take a blood thinner. However, if you take a blood thinner, be sure to check with your health care provider before taking acetaminophen as prolonged or high doses of acetaminophen may cause bleeding. Report any signs of bleeding to your doctor if you take a blood thinner.
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Acetaminophen vs paracetamol: What do you need to know?
Acetaminophen (Tylenol) found in the U.S is the same medicine as paracetamol (Panadol) used throughout many regions of the world, including Europe, Australia, India and New Zealand. Acetaminophen and paracetamol are the generic names of medicines used to treat mild pain, headache and fever. Continue reading
What is paracetamol / Panadol called in the US?
Paracetamol is known as acetaminophen in the U.S. Acetaminophen relieves mild-to-moderate pain, headache and fever. It's available over-the-counter as brand names such as Tylenol, Mapap or Panadol, and also as generics and store-specific brands. There are no differences in the chemical or therapeutics uses of acetaminophen and paracetamol, although recommended doses or available products may differ between countries. Continue reading
Advil (ibuprofen) & Tylenol (acetaminophen) together, safe?
Yes, it is safe to take ibuprofen (Advil) and acetaminophen (Tylenol) together if you need to for extra pain relief, such as for a dental extraction. Taking ibuprofen and acetaminophen together works better to relieve pain than taking ibuprofen and acetaminophen separately. This is because they work in different ways with few side effects. Continue reading
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