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What are the different brands of methotrexate?

Medically reviewed by Judith Stewart, BPharm. Last updated on Oct 31, 2024.

Official Answer by Drugs.com

What dosage forms are available? What conditions do they treat?

The different brands of methotrexate are Jylamvo, Otrexup, Rasuvo, Trexall, and Xatmep.

Methotrexate is a prescription medicine used to treat certain types of cancer, severe psoriasis, and severe rheumatoid arthritis. Methotrexate is available in a number of different dosage forms including subcutaneous injection (auto injector), oral tablets, oral solution, and injection.

Subcutaneous Injection (Auto Injector)

Auto injectors are designed for easy self-administration of a subcutaneous injection into the thigh or abdomen. Methotrexate subcutaneous injection is used once weekly for the treatment of:

Oral Tablets

Methotrexate oral tablets are used once weekly for the treatment of:

Methotrexate oral tablets are also used are used as a course of treatment for patients with certain cancers, including acute lymphoblastic leukemia (ALL), choriocarcinoma and similar trophoblastic diseases, Burkitt's tumor, and mycosis fungoides (cutaneous T cell lymphoma).

Oral Solution

Xatmep is a ready-to-use oral solution that eliminates the need for needles or the crushing of tablets, allowing for easier dosing in pediatric patients. Xatmep is used for the treatment of:

Jylamvo is ready-to-use oral solution providing an alternative treatment option for patients who struggle with swallowing pills. Jylamvo is used for the treatment of:

Injection

Methotrexate is also available as an injection and may be administered via the intramuscular, intravenous, intra-arterial or intrathecal routes. Methotrexate injection is used for the treatment of certain cancers, severe psoriasis, adult rheumatoid arthritis, and polyarticular juvenile idiopathic arthritis.

See Methotrexate Dosage

Related questions

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How long does it take for methotrexate to work?

Methotrexate can start working for rheumatoid arthritis within 3 to 6 weeks and symptoms continue to improve over 3 months. For other people it might take a few months before they notice any improvement in their rheumatoid arthritis symptoms. Continue reading

Does methotrexate cause weight gain?

​Methotrexate was shown to cause a modest amount of weight gain over 6 months, in a study measuring weight changes in people with rheumatoid arthritis. Continue reading

How do I know if methotrexate is working for rheumatoid arthritis?

To tell if methotrexate treatment is working for your rheumatoid arthritis your doctor will conduct regular blood tests and check-ups. You can also keep a track of your symptoms and looks for signs of improvement. Imaging tests, such as x-rays and musculoskeletal ultrasound (MSUS), may be used. Continue reading

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