What is the difference between Cabometyx and Cometriq?
Cabometyx and Cometriq are two brand name drugs that both contain the same active ingredient cabozantinib, a kinase inhibitor used to treat certain types of cancer. Cabozantinib inhibits multiple tyrosine kinases, including the MET, AXL and VEGF receptors.
Cabometyx and Cometriq are taken once per day and are both marketed by Exelixis in the US.
The two drugs are not bioequivalent however. That is to say, you can’t switch between the two brands.
Cabometyx and Cometriq come in different oral formulations and are used to treat different types of cancer
| Cabometyx | Cometriq | |
| Marketed since | 2016 | 2012 |
| Dosage form | Tablets | Capsules |
| Strength | 20, 40 and 60 mg | 20 and 80 mg |
| Used to treat |
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References
- Food and Drug Administration (FDA). Highlights of Prescribing Information. Cabometyx. September 2021. [Accessed September 24, 2021]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/208692s012lbl.pdf.
- Food and Drug Administration (FDA). Highlights of Prescribing Information. Cometriq. November 2020. [Accessed June 16, 2021]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/203756s009lbl.pdf.
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