Skip to main content

When is the best time to take Lexapro? Morning vs Night Dosing

Medically reviewed by Carmen Pope, BPharm. Last updated on Aug 7, 2025.

Official Answer by Drugs.com

Lexapro (escitalopram) is usually taken once a day and can be taken either in the morning or at night.

Best time to take Lexapro:

How to switch Lexapro from nighttime to morning dosing:

If you currently take Lexapro at bedtime and want to change to the morning, simply skip your nighttime dose and begin taking it the following morning. Continue with a morning dosing schedule thereafter.

Key considerations for Lexapro dosing schedule:

References

Read next

Why does Lexapro cause weight gain? Complete Patient Guide

Lexapro weight gain affects up 25 % to 41% of patients who take this antidepressant medication, although weight gain tends to be minimal, with an average gain of approximately 1 % to 3.7%. The weight gain associated with Lexapro occurs primarily due to the drug's mechanism of action on serotonin levels in the brain. When Lexapro blocks the serotonin transporter, it successfully increases serotonin availability to help treat depression and anxiety, but this same action can trigger unwanted changes in appetite and metabolism.

Continue reading

How long does it take for Lexapro to work?

Even though it takes Lexapro only a few hours to increase serotonin levels within the brain, it may take several weeks to start working. Signs that Lexapro has started working include an improvement in your sleep, energy, or appetite. In some, this may happen in as little as 1 to 2 weeks. Relief from symptoms, such as a depressed mood or a lack of interest in activities you used to enjoy, may take up to 6 to 8 weeks to fully improve. Continue reading

Does Lexapro cause night sweats?

Lexapro can cause night sweats and increased sweating overall (night and day) was one of the most common side effects reported with Lexapro, reported by 3% to 8% (depending on the dose) of people. Although night sweats can be worrisome, they usually diminish with time as your body and brain adjust to the medication. Continue reading

See also:

Related medical questions

Drug information

Related support groups