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Can Anoro Ellipta and Breo Ellipta be used together?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on March 23, 2023.

Official answer


Do not use Breo Ellipta (fluticasone furoate and vilanterol) in combination with Anoro Ellipta (umeclidinium and vilanterol) as both medications contain vilanterol, a long-acting inhaled beta agonist (LABA), and the combined use may lead to a risk of dangerous overdose. Only use the Breo or Anoro dose prescribed for you by your doctor.

Both Anoro and Breo are used for the maintenance treatment of patients with chronic obstructive pulmonary disease (COPD). Breo Ellipta is used to treat asthma in adults.

Excessive use of long-acting beta agonists (LABAs) like vilanterol may lead to a risk of heart side effects and possible death. Examples of other LABAs include: salmeterol, formoterol fumarate, arformoterol tartrate, and indacaterol.

Combining long-acting beta agonists medications may lead to certain serious side effects such:

  • fast heart rate
  • elevated blood pressure
  • abnormal heart rhythm.

Discuss these side effects with your doctor. Tell your doctor if you have a history of high blood pressure, abnormal heart rhythms or heart disease.


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