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In the US, Riociguat (riociguat systemic) is a member of the drug class vasodilators and is used to treat Pulmonary Hypertension.

US matches:

CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories


Treatment of pulmonary hypertension

Direct stimulator of the soluble guanylate cyclase (sGC)

Chemical Name

Methyl N-(4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo=[3,4-b]pyridin-3-yl]pyrimidin-5-yl)-N-methylcarbamate (WHO)

Foreign Names

  • Riociguatum (Latin)
  • Riociguat (German)
  • Riociguat (French)
  • Riociguat (Spanish)

Generic Names

  • Riociguat (OS: JAN, USAN)
  • BAY-63-2521 (IS)
  • Riociguat (PH: JP XVI)

Brand Names

  • Adempas
    Bayer, Belgium; Bayer, Canada; Bayer, Chile; Bayer, Denmark; Bayer, United Kingdom; Bayer, Croatia (Hrvatska); Bayer, Ireland; Bayer, Iceland; Bayer, Italy; Bayer, Poland; Bayer, Romania; Bayer, Sweden; Bayer, Slovenia; Bayer HealthCare, Finland; Bayer HealthCare, Singapore; Bayer HealthCare, United States; Bayer Pharma, Austria; Bayer Pharma, Cyprus; Bayer Santé, France; Bayer Vital, Germany; Bayer Yakuhin, Japan


ISInofficial Synonym
JANJapanese Accepted Name
OSOfficial Synonym
PHPharmacopoeia Name
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

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