Zoloft Interactions
There are 673 drugs known to interact with Zoloft (sertraline), along with 10 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 157 are major, 511 are moderate, and 5 are minor.
- View all 673 medications that may interact with Zoloft
- View Zoloft alcohol/food interactions (1)
- View Zoloft disease interactions (10)
Most frequently checked interactions
View interaction reports for Zoloft (sertraline) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- albuterol
- Ambien (zolpidem)
- aspirin
- Ativan (lorazepam)
- atorvastatin
- clonazepam
- gabapentin
- hydroxyzine
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- Lipitor (atorvastatin)
- lisinopril
- melatonin
- metformin
- omeprazole
- prednisone
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
Zoloft alcohol/food interactions
There is 1 alcohol/food interaction with Zoloft (sertraline).
Zoloft disease interactions
There are 10 disease interactions with Zoloft (sertraline) which include:
- depression
- hyponatremia
- glaucoma
- liver disease
- mania
- platelet function
- seizure disorders
- SIADH
- renal dysfunction
- weight loss
Report options
More about Zoloft (sertraline)
- Zoloft consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (1,972)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: selective serotonin reuptake inhibitors
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
