Sunitinib and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with sunitinib which include:
SUNItinib ↔ food
Moderate Food Interaction
SUNItinib may be taken with or without food. If you are receiving therapy with SUNItinib you should avoid the regular consumption of large amounts of grapefruits and grapefruit juice. Grapefruit can raise the levels of SUNItinib in your body and lead to increased side effects. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
High Blood Pressure (Hypertension)
Moderate Potential Hazard, Moderate plausibility
sunitinib - hypertension
The use of sunitinib has been associated with hypertension and it should be used with caution in patients with elevated blood pressure. Therapy with sunitinib should be withheld in case of severe hypertension and appropriate measures should be taken to correct the blood pressure to acceptable readings. Close monitoring of blood pressure is recommended.
sunitinib drug Interactions
There are 446 drug interactions with sunitinib
sunitinib disease Interactions
There are 12 disease interactions with sunitinib which include:
- Liver Disease
- Adrenal Toxicity
- Cardiovascular Events
- Dermatologic Toxicities
- Hemorrhagic Events
- Hypertension
- Hypoglycemia
- Onj
- Proteinuria
- Qt Prolongation
- Thyroid Abnormality
- Sunitinib – Renal Disease
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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