Pentobarbital and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with pentobarbital.
Pentobarbital Alcohol (Ethanol)
Major Drug Interaction
Ask your doctor before using PENTobarbital together with ethanol (alcohol), this can add to dizziness, drowsiness and other side effects of PENTobarbital. Be careful if you drive or do activities that require you to be awake and alert. Talk with your doctor before using any medications together, or drinking alcohol with PENTobarbital. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
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Pentobarbital High Blood Pressure (Hypertension)
Major Potential Hazard, Moderate plausibility
barbiturates IV - cardiovascular
The intravenous administration of barbiturates may produce severe cardiovascular reactions such as bradycardia, hypertension, or vasodilation with fall in blood pressure, particularly during rapid infusion. Parenteral therapy with barbiturates should be administered cautiously in patients with hypertension, hypotension, or cardiac disease. The intravenous administration of barbiturates should be reserved for emergency treatment of acute seizures or for anesthesia.
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Pentobarbital drug interactions
There are 554 drug interactions with pentobarbital.
Pentobarbital disease interactions
There are 13 disease interactions with pentobarbital which include:
- acute alcohol intoxication
- drug dependence
- liver disease
- porphyria
- rash
- respiratory depression
- cardiovascular
- prolonged hypotension
- adrenal insufficiency
- depression
- hematologic toxicity
- osteomalacia
- paradoxical reactions
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
