Skip to main content

Mirtazapine and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with mirtazapine.


Mirtazapine Food

Moderate Food Interaction

Alcohol can increase the nervous system side effects of mirtazapine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with mirtazapine. Do not use more than the recommended dose of mirtazapine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Switch to professional interaction data


Mirtazapine High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)

Moderate Potential Hazard, Moderate plausibility

mirtazapine - hyperlipidemia

Mirtazapine may significantly elevate serum triglyceride and total cholesterol levels. Patients with preexisting hyperlipidemia may require closer monitoring during mirtazapine therapy, and adjustments made accordingly in their lipid-lowering regimen.


  1. Smith WT, Glaudin V, Panagides J, Gilvary E (1990) "Mirtazapine vs. amitriptyline vs. placebo in the treatment of major depressive disorder." Psychopharmacol Bull, 26, p. 191-6
  2. (2001) "Product Information. Remeron (mirtazapine)." Organon
  3. Davis R, Wilde MI (1996) "Mirtazapine: a review of its pharmacology and therapeutic potential in the management of major depression." Cns Drugs, 5, p. 389-402
  4. Montgomery SA (1995) "Safety of mirtazapine: a review." Int Clin Psychopharmacol, 10(suppl 4, p. 37-45
View all 4 references

Mirtazapine drug interactions

There are 651 drug interactions with mirtazapine.

Mirtazapine disease interactions

There are 13 disease interactions with mirtazapine which include:

Report options

QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.