Hydrochlorothiazide / methyldopa and Alcohol / Food Interactions
There are 3 alcohol/food/lifestyle interactions with hydrochlorothiazide / methyldopa which include:
hydroCHLOROthiazide ↔ Alcohol (Ethanol)
Moderate Drug Interaction
Hydrochlorothiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
methyldopa ↔ multivitamins with minerals
Moderate Drug Interaction
Methyldopa and multivitamin with minerals should not be taken orally at the same time. Products that contain iron may interfere with the absorption of methyldopa and reduce its effectiveness. You should separate the dosing of these medications by as much as possible. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
High Cholesterol (Hyperlipoproteinemia, Hypertriglyceridemia, Sitosterolemia)
Moderate Potential Hazard, Moderate plausibility
thiazides - hyperlipidemia
Thiazide diuretics may increase serum triglyceride and cholesterol levels, primarily LDL and VLDL. Whether these effects are dose-related and sustained during chronic therapy are unknown. Patients with preexisting hyperlipidemia may require closer monitoring during thiazide therapy, and adjustments made accordingly in their lipid-lowering regimen
- Ames RP "A comparison of blood lipid and blood pressure responses during the treatment of systemic hypertension with indapamide and with thiazides." Am J Cardiol 77 (1996): b12-6
- Slotkoff L "Clinical efficacy and safety of indapamide in the treatment of edema." Am Heart J 106 (1983): 233-7
- Freis ED "The efficacy and safety of diuretics in treating hypertension." Ann Intern Med 122 (1995): 223-6
hydrochlorothiazide / methyldopa drug Interactions
There are 951 drug interactions with hydrochlorothiazide / methyldopa
hydrochlorothiazide / methyldopa disease Interactions
There are 10 disease interactions with hydrochlorothiazide / methyldopa which include:
- Electrolyte Losses
- Liver Disease
- Lupus Erythematosus
- Renal Function Disorders
- Thyroid Function Tests
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Do not stop taking any medications without consulting your healthcare provider.