Hydralazine/isosorbide dinitrate and Alcohol/Food Interactions
There are 3 alcohol/food/lifestyle interactions with hydralazine / isosorbide dinitrate.
hydrALAZINE Alcohol (Ethanol)
Moderate Drug Interaction
Isosorbide dinitrate may add to the blood pressure lowering effects of hydrALAZINE. You may need a dose adjustment or more frequent monitoring of your blood pressure to safely use both medications. Contact your doctor if you experience dizziness, weakness, fatigue, lightheadedness, headache, flushing, fainting, or a rapid pulse or heart rate. Avoid driving or operating hazardous machinery until you know how these medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hydrALAZINE Alcohol (Ethanol)
Moderate Drug Interaction
HydrALAZINE and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
isosorbide dinitrate Alcohol (Ethanol)
Moderate Drug Interaction
Isosorbide dinitrate and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Hydralazine/isosorbide dinitrate drug interactions
There are 435 drug interactions with hydralazine / isosorbide dinitrate.
Hydralazine/isosorbide dinitrate disease interactions
There are 13 disease interactions with hydralazine / isosorbide dinitrate which include:
- bone marrow suppression
- coronary artery disease
- lupus erythematosus
- valvular heart disease
- AMI
- anemia
- hemodialysis
- hypotension
- intracranial pressure
- cerebral vasculopathy
- renal dysfunction
- hypertrophic cardiomyopathy
- glaucoma
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.