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Denaze (chlorpheniramine / methscopolamine / phenylephrine) and Alcohol / Food Interactions

There are 2 alcohol/food/lifestyle interactions with Denaze (chlorpheniramine / methscopolamine / phenylephrine) which include:

Moderate

chlorpheniramine ↔ food

Moderate Food Interaction

Consumer information for this interaction is not currently available.

GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.

MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

References

  1. Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
  2. "Product Information. Fycompa (perampanel)." Eisai Inc, Teaneck, NJ.
  3. Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7
  4. "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc, Rockville, MD.
View all 4 references
Moderate

High Blood Pressure (Hypertension)

Minor Potential Hazard, Low plausibility

anticholinergics - hypertension

Cardiovascular effects of anticholinergics may exacerbate hypertension. Therapy with anticholinergic agents should be administered cautiously in patients with hypertension.

References

  1. "Product Information. Marezine (cyclizine)." Glaxo Wellcome, Research Triangle Park, NC.
  2. "Product Information. Benadryl (diphenhydramine)." Parke-Davis, Morris Plains, NJ.
  3. Valentin N, Staffeldt H, Kyst A "Effect of i.v. atropine on cardiac rhythm, heart rate, blood pressure and airway secretion during isoflurane anaesthesia." Acta Anaesthesiol Scand 28 (1984): 621-4
  4. "Product Information. Cogentin (benztropine)." Merck & Co, Inc, West Point, PA.
  5. "Product Information. Antivert (meclizine)." Roerig Division, New York, NY.
  6. "Product Information. Artane (trihexyphenidyl)." Lederle Laboratories, Wayne, NJ.
  7. "Product Information. Atropine Sulfate Injection, USP (atropine)." ESI Lederle Generics, Philadelphia, PA.
View all 7 references

Denaze (chlorpheniramine / methscopolamine / phenylephrine) drug interactions

There are 467 drug interactions with Denaze (chlorpheniramine / methscopolamine / phenylephrine)

Denaze (chlorpheniramine / methscopolamine / phenylephrine) disease interactions

There are 25 disease interactions with Denaze (chlorpheniramine / methscopolamine / phenylephrine) which include:

More about Denaze (chlorpheniramine / methscopolamine / phenylephrine)

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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