Avatrombopag and Alcohol/Food Interactions
There is 1 alcohol/food/lifestyle interaction with avatrombopag.
Avatrombopag Food/Lifestyle
Moderate Food Interaction
ADJUST DOSING INTERVAL: Food reduces the variability in oral absorption and bioavailability of avatrombopag. According to the product labeling, avatrombopag peak plasma concentration (Cmax) and systemic exposure (AUC) were not affected when administered with either a low-fat (500 calories; 3 g fat, 15 g proteins, 108 g carbohydrates) or high-fat (918 calories; 59 g fat, 39 g proteins, 59 g carbohydrates) meal. However, the variability of avatrombopag exposure was reduced by 40% to 60% with food, and the time to reach Cmax was delayed by 0 to 2 hours relative to the fasted state.
MANAGEMENT: To ensure consistent absorption and plasma drug levels, avatrombopag should be taken with food.
References (1)
- (2018) "Product Information. Doptelet (avatrombopag)." Dova Pharmaceuticals
Switch to consumer interaction data
Avatrombopag drug interactions
There are 88 drug interactions with avatrombopag.
Avatrombopag disease interactions
There are 2 disease interactions with avatrombopag which include:
Report options
More about avatrombopag
- avatrombopag consumer information
- Check interactions
- Compare alternatives
- Reviews (10)
- Side effects
- Dosage information
- During pregnancy
- Drug class: platelet-stimulating agents
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Decadron
Decadron is used for addison's disease, adrenal insufficiency, adrenocortical insufficiency ...
Dexamethasone Intensol
Dexamethasone Intensol is used for addison's disease, adrenal insufficiency, adrenocortical ...
Nplate
Nplate is used to prevent bleeding episodes in people with chronic immune thrombocytopenic purpura ...
Deltasone
Deltasone is used for acute lymphocytic leukemia, adrenocortical insufficiency, allergic reactions ...
Promacta
Promacta is used to prevent bleeding episodes in patients with chronic immune (idiopathic) ...
Kenalog-40
Kenalog-40 is a long-acting corticosteroid injection for intramuscular (into the muscle) or ...
Eltrombopag
Eltrombopag is used for aplastic anemia, immune thrombocytopenia, thrombocytopenia ...
Cortisone
Cortisone is used for adrenal insufficiency, ankylosing spondylitis, berylliosis, bursitis ...
Triamcinolone
Triamcinolone is used to treat allergies, skin conditions, ulcerative colitis, and arthritis. Learn ...
Dexamethasone
Dexamethasone is used to treat inflammatory conditions such as allergies, skin conditions ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
