• Zosyn powder for solution for injection, Pfizer
  2.25 gram, vial, 10 count (NDC 00206-8852-16)

• • Apotex has piperacillin/tazobactam on shortage due to regulatory delays.
  • AuroMedics and Sandoz could not provide a reason for the shortage.
  • Fresenius Kabi has piperacillin/tazobactam on shortage due to increased demand.
  • Mylan Institutional launched piperacillin/tazobactam 3.375 gram and 4.5 gram vials in early-June 2016.
  • Pfizer has Zosyn single dose vials and piperacillin/tazobactam on shortage due to manufacturing delays.
  • Sagent has piperacillin/tazobactam on shortage due to increased demand.
  • Sandoz has piperacillin/tazobactam available for contracted customers.
  • WG Critical Care states the reason for the shortage is increased demand.
  • FDA in conjunction with SteriMax was allowing temporary importation of piperacillin/tazobactam 3.375 gram, 4.5 gram, and 40.5 gram vials from Canada. This was being distributed through X-Gen Pharmaceuticals. These are no longer being imported with the launch of the products from X-Gen. The product codes on these items will not be recognized by U.S. systems so institutions will need to implement alternative plans to assure the dose is being given correctly. More information can be found here on the FDA site.
  • Wockhardt has piperacillin/tazobactam injection available.
  • X-Gen has piperacillin/tazobactam injection available.

• Zosyn solution for injection, Baxter
  2.25 gram, 50 mL frozen premixed bag, 24 count (NDC 00206-8860-02)
  3.375 gram, 50 mL frozen premixed bag, 24 count (NDC 00206-8861-02)
  4.5 gram, 50 mL frozen premixed bag, 12 count (NDC 00206-8862-02)

Estimated Resupply Dates

• • Apotex has piperacillin/tazobactam 3.375 gram, 4.5 gram, and 40.5 gram vials on back order and the company estimates a release date of early-August 2017 for the 3.375 gram and 4.5 gram vials and mid-August 2017 for the 40.5 gram vials.
  • AuroMedics has piperacillin/tazobactam on intermittent back order and the company is releasing product as it becomes available. Check wholesalers for inventory.  
  • Fresenius Kabi has piperacillin/tazobactam 40.5 gram vials on back order and the company estimates a release date of mid-July 2017.
  • Pfizer has Zosyn 2.25 gram vials, 3.375 gram vials, 4.5 gram vials, and 40.5 gram vials on back order and the company estimates a release date of January 2018.
  • Sagent has piperacillin/tazobactam 4.5 gram vials on allocation.
  • Sandoz has piperacillin/tazobactam 2.25 gram (NDC 00781-3110-85) and 4.5 gram (NDC 00781-3367-95) vials on back order and the company estimates a release date of mid-July 2017.
  • WG Critical Care has piperacillin/tazobactam 3.375 gram and 4.5 gram vials on back order and the company estimates a release date of August 2017.