Vioxx Interactions
There are 302 drugs known to interact with Vioxx (rofecoxib). Of the total drug interactions, 65 are major, and 237 are moderate.
- View all 302 medications that may interact with Vioxx
Most frequently checked interactions
View interaction reports for Vioxx (rofecoxib) and the medicines listed below.
- Ambien (zolpidem)
- amitriptyline
- amoxicillin
- Celebrex (celecoxib)
- Cymbalta (duloxetine)
- diclofenac
- Flexeril (cyclobenzaprine)
- furosemide
- gabapentin
- ibuprofen
- Lipitor (atorvastatin)
- lisinopril
- Lyrica (pregabalin)
- meloxicam
- metformin
- methotrexate
- Mobic (meloxicam)
- naproxen
- omeprazole
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vicodin (acetaminophen / hydrocodone)
- Vitamin D3 (cholecalciferol)
- Voltaren Arthritis Pain Gel (diclofenac topical)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Report options
More about Vioxx (rofecoxib)
- Vioxx consumer information
- Compare alternatives
- Reviews (55)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: cox-2 inhibitors
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Ubrelvy
Ubrelvy (ubrogepant) tablets are used for the acute treatment of migraine. Includes Ubrelvy side ...
Nurtec ODT
Nurtec ODT (rimegepant) is used to treat acute migraines and prevent episodic migraines, by ...
Qulipta
Qulipta is used to help prevent episodic or chronic migraine headaches in adults. Qulipta is an ...
Paracetamol
Paracetamol (Panadol, Calpol, Alvedon) is a widely used over-the-counter painkiller and fever ...
Diclofenac
Diclofenac is a nonsteroidal anti-inflammatory drug used to treat pain and inflammation associated ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Amitriptyline
Amitriptyline is a tricyclic antidepressant used to treat depression and, off-label, conditions ...
Tramadol
Tramadol is an opioid medication that may be used to treat moderate to moderately severe chronic ...
Duloxetine
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant used to ...
Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
