Vioxx Interactions
There are 302 drugs known to interact with Vioxx (rofecoxib). Of the total drug interactions, 65 are major, and 237 are moderate.
- View all 302 medications that may interact with Vioxx
Most frequently checked interactions
View interaction reports for Vioxx (rofecoxib) and the medicines listed below.
- Ambien (zolpidem)
- amitriptyline
- amoxicillin
- Celebrex (celecoxib)
- Cymbalta (duloxetine)
- diclofenac
- Flexeril (cyclobenzaprine)
- furosemide
- gabapentin
- ibuprofen
- Lipitor (atorvastatin)
- lisinopril
- Lyrica (pregabalin)
- meloxicam
- metformin
- methotrexate
- Mobic (meloxicam)
- naproxen
- omeprazole
- prednisone
- Singulair (montelukast)
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Vicodin (acetaminophen / hydrocodone)
- Vitamin D3 (cholecalciferol)
- Voltaren Arthritis Pain Gel (diclofenac topical)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Report options
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More about Vioxx (rofecoxib)
- Vioxx consumer information
- Compare alternatives
- Reviews (55)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: cox-2 inhibitors
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
