Vioxx Drug Interactions
Currently displaying a list of 302 drugs known to interact with Vioxx (rofecoxib).
- 65 major drug interactions
- 237 moderate drug interactions
Medications known to interact with Vioxx
Note: Showing generic names only.
- abciximab
- acebutolol
- acetohexamide
- adefovir
- alendronate
- aliskiren
- alosetron
- alteplase
- amikacin
- amikacin liposome
- amiloride
- aminophylline
- anagrelide
- anisindione
- anistreplase
- antithrombin (recombinant)
- antithrombin iii
- apixaban
- ardeparin
- argatroban
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- aspirin
- atenolol
- azilsartan medoxomil
- balsalazide
- baricitinib
- bedaquiline
- benazepril
- bendamustine
- bendroflumethiazide
- benzthiazide
- betamethasone
- betaxolol
- betrixaban
- bisoprolol
- bivalirudin
- black cohosh
- botulism immune globulin
- brentuximab
- bromfenac
- budesonide
- bumetanide
- calaspargase pegol
- candesartan
- cangrelor
- cannabidiol
- caplacizumab
- captopril
- carteolol
- carvedilol
- chlorothiazide
- chlorpromazine
- chlorpropamide
- chlorthalidone
- cidofovir
- cilostazol
- cinoxacin
- ciprofloxacin
- clofarabine
- clopidogrel
- cortisone
- cyclosporine
- cytomegalovirus immune globulin
- dabigatran
- daclizumab
- dalteparin
- danaparoid
- daptomycin
- deferasirox
- defibrotide
- deflazacort
- delafloxacin
- desirudin
- desmopressin
- dexamethasone
- diatrizoate
- diclofenac
- diclofenac topical
- dicumarol
- diflunisal
- dimethyl fumarate
- dipyridamole
- diroximel fumarate
- droperidol
- drospirenone
- duloxetine
- edoxaban
- efavirenz
- enalapril
- enalaprilat
- enoxacin
- enoxaparin
- entecavir
- epirubicin
- eplerenone
- epoprostenol
- eprosartan
- eptifibatide
- erlotinib
- esmolol
- ethacrynic acid
- etidronate
- etodolac
- etranacogene dezaparvovec
- everolimus
- exenatide
- fenfluramine
- fenoprofen
- fezolinetant
- fidanacogene elaparvovec
- flucytosine
- fludrocortisone
- flurbiprofen
- fondaparinux
- fosinopril
- furosemide
- ganciclovir
- gatifloxacin
- gemifloxacin
- gentamicin
- ginkgo
- glimepiride
- glipizide
- glyburide
- grepafloxacin
- ibandronate
- ibuprofen
- icosapent
- idelalisib
- iloprost
- immune globulin intravenous
- immune globulin intravenous and subcutaneous
- indapamide
- indomethacin
- inotersen
- interferon beta-1a
- interferon beta-1b
- iodamide
- iodipamide
- iodixanol
- iohexol
- iomeprol
- iopamidol
- iopromide
- iothalamate
- ioversol
- ioxaglate
- ioxilan
- irbesartan
- isoniazid
- labetalol
- landiolol
- leflunomide
- lepirudin
- levobupivacaine
- levofloxacin
- levoketoconazole
- lisinopril
- lithium
- lomefloxacin
- lomitapide
- losartan
- lurbinectedin
- macimorelin
- meclofenamate
- mefenamic acid
- melatonin
- meloxicam
- mesalamine
- metformin
- methotrexate
- methoxyflurane
- methyclothiazide
- methylprednisolone
- metolazone
- metoprolol
- metrizamide
- mifepristone
- mipomersen
- mirtazapine
- moexipril
- monomethyl fumarate
- moxifloxacin
- nabumetone
- nadolol
- nalidixic acid
- naltrexone
- naproxen
- nateglinide
- nebivolol
- netilmicin
- nintedanib
- norfloxacin
- ofloxacin
- olanzapine
- olmesartan
- olsalazine
- omega-3 polyunsaturated fatty acids
- oxaliplatin
- oxaprozin
- oxtriphylline
- pamidronate
- pegaspargase
- peginterferon beta-1a
- pemetrexed
- penbutolol
- perindopril
- pexidartinib
- phenylbutazone
- pimozide
- pindolol
- piroxicam
- plazomicin
- polyethylene glycol 3350 with electrolytes
- polythiazide
- prasugrel
- prednisolone
- prednisone
- propranolol
- protein c
- ramelteon
- ramipril
- rasagiline
- remdesivir
- repaglinide
- respiratory syncytial virus immune globulin
- reteplase
- rho (d) immune globulin
- rifampin
- risedronate
- rivaroxaban
- roflumilast topical
- ropinirole
- sirolimus
- sotalol
- sparfloxacin
- sparsentan
- spironolactone
- stiripentol
- streptokinase
- streptomycin
- sulfasalazine
- sulfinpyrazone
- sulindac
- tacrolimus
- tasimelteon
- telbivudine
- telmisartan
- temsirolimus
- tenecteplase
- tenofovir alafenamide
- tenofovir disoproxil
- teriflunomide
- theophylline
- thioguanine
- ticagrelor
- ticlopidine
- tiludronate
- timolol
- tinzaparin
- tirofiban
- tizanidine
- tobramycin
- tofacitinib
- tolazamide
- tolbutamide
- tolmetin
- torsemide
- trabectedin
- trandolapril
- treprostinil
- triamcinolone
- triamcinolone ophthalmic
- triamterene
- trichlormethiazide
- trovafloxacin
- valacyclovir
- valganciclovir
- valoctocogene roxaparvovec
- valsartan
- vamorolone
- vancomycin
- vasopressin
- voclosporin
- vorapaxar
More about Vioxx (rofecoxib)
- Vioxx consumer information
- Check interactions
- Compare alternatives
- Reviews (55)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: cox-2 inhibitors
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.