Xarelto Drug Interactions
Currently displaying a list of 386 drugs known to interact with Xarelto (rivaroxaban).
- 135 major drug interactions
- 210 moderate drug interactions
- 41 minor drug interactions
Medications known to interact with Xarelto
Note: Showing generic names only.
A
- abametapir topical
- abciximab
- abrocitinib
- acalabrutinib
- adagrasib
- adalimumab
- ado-trastuzumab emtansine
- aducanumab
- alefacept
- alemtuzumab
- alpelisib
- alteplase
- aminoglutethimide
- amiodarone
- amobarbital
- amprenavir
- anacaulase topical
- anagrelide
- anakinra
- anisindione
- anistreplase
- antithrombin (recombinant)
- antithrombin iii
- apalutamide
- apixaban
- aprepitant
- ardeparin
- argatroban
- armodafinil
- asciminib
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- aspirin
- atazanavir
- avacopan
- avapritinib
- azithromycin
B
- belzutifan
- bepridil
- berotralstat
- betrixaban
- bexarotene
- bimekizumab
- bismuth subsalicylate
- bivalirudin
- boceprevir
- bosentan
- brigatinib
- brodalumab
- bromfenac
- bromfenac ophthalmic
- butabarbital
- butalbital
C
- cabozantinib
- calaspargase pegol
- canakinumab
- cangrelor
- caplacizumab
- capmatinib
- capsicum
- carbamazepine
- celecoxib
- cenobamate
- ceritinib
- chamomile
- chloramphenicol
- choline salicylate
- cilostazol
- cimetidine
- citalopram
- clarithromycin
- clomipramine
- clopidogrel
- clotrimazole
- clove
- coagulation factor x
- cobicistat
- collagenase clostridium histolyticum
- conivaptan
- crizotinib
- cyclosporine
D
- dabigatran
- dabrafenib
- daclatasvir
- dalteparin
- danaparoid
- danicopan
- daridorexant
- darolutamide
- darunavir
- dasatinib
- deferasirox
- defibrotide
- delavirdine
- deoxycholic acid
- desirudin
- desvenlafaxine
- dexamethasone
- dexfenfluramine
- dextran 1
- dextran, high molecular weight
- dextran, low molecular weight
- diclofenac
- diclofenac ophthalmic
- diclofenac topical
- dicumarol
- diflunisal
- diltiazem
- dipyridamole
- divalproex sodium
- donanemab
- dong quai
- dronedarone
- drotrecogin alfa
- duloxetine
- duvelisib
E
- echinacea
- edoxaban
- efavirenz
- elacestrant
- elagolix
- eliglustat
- elranatamab
- emapalumab
- enasidenib
- encorafenib
- enoxaparin
- entrectinib
- enzalutamide
- epcoritamab
- epoprostenol
- eptifibatide
- erdafitinib
- erythromycin
- escitalopram
- etodolac
- etravirine
- evening primrose
F
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fenoprofen
- fenugreek
- feverfew
- fexinidazole
- flibanserin
- fluconazole
- fluoxetine
- flurbiprofen
- flurbiprofen ophthalmic
- fluvoxamine
- fondaparinux
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- fostemsavir
- futibatinib
G
- garlic
- gilteritinib
- ginger
- ginkgo
- ginseng
- givinostat
- glasdegib
- glofitamab
- golimumab
- griseofulvin
- guselkumab
H
I
- ibritumomab
- ibrutinib
- ibuprofen
- icosapent
- idelalisib
- iloprost
- imatinib
- indinavir
- indomethacin
- infliximab
- inotersen
- iodine i 131 tositumomab
- ipilimumab
- isavuconazonium
- itraconazole
- ivacaftor
- ivosidenib
K
L
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lecanemab
- lefamulin
- lenacapavir
- leniolisib
- lepirudin
- letermovir
- levetiracetam
- levoketoconazole
- levomilnacipran
- lomitapide
- lonafarnib
- lonapegsomatropin
- lorlatinib
M
- magnesium salicylate
- maribavir
- mavacamten
- mavorixafor
- meclofenamate
- mefenamic acid
- meloxicam
- mephobarbital
- methyl salicylate topical
- mibefradil
- miconazole
- midostaurin
- mifepristone
- milnacipran
- mitapivat
- mitotane
- mobocertinib
- modafinil
- momelotinib
- mosunetuzumab
N
- nabumetone
- nafcillin
- naproxen
- nefazodone
- nelfinavir
- nemolizumab
- nepafenac ophthalmic
- neratinib
- nevirapine
- nifedipine
- nilotinib
- nintedanib
- niraparib
O
- olutasidenib
- omacetaxine
- omaveloxolone
- omega-3 polyunsaturated fatty acids
- oritavancin
- oteseconazole
- oxaprozin
- oxcarbazepine
P
- pacritinib
- panobinostat
- paroxetine
- pegaspargase
- pemigatinib
- pentobarbital
- pentosan polysulfate sodium
- pentoxifylline
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- piroxicam
- pirtobrutinib
- plasminogen, human
- plicamycin
- ponatinib
- posaconazole
- pralsetinib
- prasugrel
- pretomanid
- primidone
- protein c
Q
R
- ramucirumab
- ranolazine
- regorafenib
- repotrectinib
- resmetirom
- reteplase
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- riociguat
- ripretinib
- ritlecitinib
- ritonavir
- rofecoxib
- rolapitant
- ropeginterferon alfa-2b
- rucaparib
- ruxolitinib
S
- salsalate
- saquinavir
- sarecycline
- sarilumab
- satralizumab
- secobarbital
- secukinumab
- selpercatinib
- selumetinib
- sertraline
- sibutramine
- siltuximab
- sodium iodide i-123
- sodium iodide-i-131
- sodium salicylate
- sodium thiosalicylate
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotorasib
- st. john's wort
- stiripentol
- streptokinase
- sugammadex
- sulfinpyrazone
- sulindac
- sunitinib
- suprofen ophthalmic
- suvorexant
- suzetrigine
T
- tacrolimus
- tafasitamab
- talquetamab
- tarlatamab
- tazemetostat
- tebentafusp
- teclistamab
- tedizolid
- telaprevir
- telithromycin
- telotristat
- temsirolimus
- tenecteplase
- tepotinib
- ticagrelor
- ticlopidine
- tinzaparin
- tipranavir
- tirofiban
- tivozanib
- tocilizumab
- tolmetin
- tolvaptan
- tositumomab
- tovorafenib
- tranexamic acid
- treosulfan
- treprostinil
- trofinetide
- troglitazone
- troleandomycin
- tucatinib
- turmeric
U
V
- vadadustat
- valdecoxib
- valproic acid
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- verteporfin
- vibegron
- vilazodone
- vimseltinib
- vitamin e
- vorapaxar
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
W
Z
Xarelto disease interactions
There are 6 disease interactions with Xarelto (rivaroxaban) which include:
- bleeding
- valvular heart disease
- antiphospholipid syndrome
- hepatic impairment
- renal disease
- unstable blood pressure
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More about Xarelto (rivaroxaban)
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- Generic availability
- Support group
- FDA approval history
- Drug class: factor Xa inhibitors
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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