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Generic name: esmololES-moe-lol ]
Drug classes: Cardioselective beta blockers, Group II antiarrhythmics

Medically reviewed by on Dec 12, 2023. Written by Cerner Multum.

What is Brevibloc?

Brevibloc is used to help keep the heart beating normally in people with certain heart rhythm disorders, such as atrial fibrillation or atrial flutter.

Brevibloc is also used during surgery to help regulate blood pressure and heart rate.

Brevibloc may also be used for purposes not listed in this medication guide.

Brevibloc side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Tell your medical caregivers at once if you have:

Common side effects of Brevibloc may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


You should not use Brevibloc if you have a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker), severe heart failure, pulmonary hypertension, slow heartbeats that have caused you to faint, recently had a heart attack, or if you are receiving certain IV heart or blood pressure medications.

If you receive Brevibloc during an emergency, make sure any follow-up doctor knows you received Brevibloc.

Before taking this medicine

You should not use Brevibloc if you are allergic to it, or if you have:

Tell your doctor if you have or have ever had:

Using this medicine during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor right away if you get pregnant. Do not stop the medicine without your doctor's advice.

Ask a doctor if it is safe to breastfeed while using this medicine.

How is Brevibloc given?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

Brevibloc is given as an infusion into a vein. A healthcare provider will give you this injection.

Tell your medical caregivers if you feel any burning or pain when Brevibloc is injected.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are receiving Brevibloc.

Your blood pressure will need to be checked often and you may need medical tests to check your progress. Your blood sugar and heart function will also be checked on a regular basis.

What happens if I miss a dose?

In a medical setting you are not likely to miss a dose.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid while receiving Brevibloc?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Brevibloc?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect Brevibloc, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.