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Factor Xa inhibitors

What are Factor Xa inhibitors?

Factor Xa inhibitors are a type of anticoagulant that work by selectively and reversibly blocking the activity of clotting factor Xa, preventing clot formation. They affect both factor Xa within the blood and within a preexisting clot. They do not affect platelet aggregation. They are used for the treatment and prevention of deep vein thrombosis and acute pulmonary embolism, and to reduce the risk of stroke and embolism in people with nonvalvular atrial fibrillation.

Factor Xa is generated by both the extrinsic and intrinsic coagulation pathways and is responsible for activating prothrombin to thrombin. Factor Xa inhibitors have predictable anticoagulant effects and do not require routine monitoring, unlike some other anticoagulants.

Apixaban, edoxaban, fondaparinux, and rivaroxaban are all Factor Xa inhibitors.

List of Factor Xa inhibitors:

View by  Brand | Generic
Drug Name Reviews Avg. Ratings
Arixtra (Pro)
Generic name: fondaparinux
7 reviews
8.9
Xarelto (Pro)
Generic name: rivaroxaban
185 reviews
5.7
Eliquis (Pro)
Generic name: apixaban
151 reviews
4.9
Savaysa (Pro)
Generic name: edoxaban
2 reviews
1.0
Bevyxxa (Pro)
Generic name: betrixaban
0 reviewsAdd rating
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.