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User Reviews for Apixaban

Also known as: Eliquis

Apixaban has an average rating of 5.0 out of 10 from a total of 193 ratings on Drugs.com. 32% of those users who reviewed Apixaban reported a positive effect, while 42% reported a negative effect.

Condition Avg. Rating Reviews Compare
Prevention of Thromboembolism in Atrial Fibrillation  
4.5
92 reviews 40 medications
Pulmonary Embolism  
7.0
40 reviews 15 medications
Deep Vein Thrombosis  
4.7
35 reviews 19 medications
Deep Vein Thrombosis, Prophylaxis  
3.4
9 reviews 15 medications
Thromboembolic Stroke Prophylaxis  
3.7
8 reviews 63 medications
Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery  
4.6
5 reviews 12 medications
Venous Thromboembolism  
4.5
4 reviews 12 medications
Summary of Apixaban reviews 5.0 193 reviews

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Apixaban

Jo · Taken for 5 to 10 years April 30, 2021

For Prevention of Thromboembolism in Atrial Fibrillation: “I was put on apixaban in Jan 2016 after taking a few attacks of Paroxysmal Atrial Fibrillation (PAF) I also have a small leak at mitral valve and will be on medication for life. I was also prescribed bisoprolol to lower BP. I felt terrible as if I had chains around my ankles and was dragging them every step I took. Read up on the 2 drugs but both had similar side effects so I went to my gp in 2017 and changed the bisoprolol to atenolol. I still the side effects so I have come to the conclusion that is was the Apixaban all along causing the problems. I get abdominal pain daily and get so breathless even doing the slightest thing. I can't go out shopping as I used to do as the breathlessness is awful. My gp said my oxygen levels were fine, but I feel as if there is a giant peg on my nose and cannot get a breath. It has been worse since COVID as the masks make me feel worse. The only good thing is that I haven't had any more AFib attacks since 2017 I wonder if half the 5 mg dose 2x day would help. I am a woman of 74.”

3 / 10
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William · Taken for less than 1 month April 9, 2021

Eliquis (apixaban) for Deep Vein Thrombosis, Prophylaxis: “I am going back to my old prescription I was on for 15 years”

1 / 10
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Dan L · Taken for 5 to 10 years April 4, 2021

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “I am now 76 and I have had Atrial Fibrillation since 2006. In 2007 I got Apocard (Flecainide) 250 mg and Asaflow 160 mg, then 80 mg until 2012-2013 when I got a gastritis largely because of the Asaflow (practically Aspirin). Since 2013 I am on Eliquis 5 mg twice a day. From day one I had no adverse effects whatsoever. In the meantime I also had an ablation which really produced wonders: I reduced the Apocard to the minimum dose of 100mg and hardly get any palpitations anymore. I take large daily doses of magnesium (400-500 mg) with Vitamine B6. On days when predisposition to palpitations is higher I also take Calmday 5 mg one or twice. Other days I take Valium 10 mg (at night time).”

10 / 10
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Lindy August 5, 2020

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “Been on Eliquis a little over a month after having one Afib attack. 2.5 mg twice a day. Hate it and hate the metoprolol I am also taking. Both have exact same side effects so hard to tell which causes me problems. I had ringing in the ears before these meds but meds make it way worse. Aches all over. Kidneys hurt. Headaches most of the time. Itching. Starting to lose hair. Tingling in legs and feet. I think the metoprolol causes the frequent urination but I think so does Eliquis. When you get a printout from the Dr or pharmacy you only get a few of the side effects. I use this Drugs.com site to find out ALL side effects of any med. I have been told through the years by different Drs how well I do with pain. I felt so bad today I just cried. This stuff is poison. 68 yr old female with no other health problems. Til I started taking this poison. May look into natural treatment before this stuff is awful. So sick.”

1 / 10
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dk9766 April 3, 2020

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “I have A-Fib and had a pacemaker installed in December 2019, at that time my doctor had told me as soon as I am healed from the pacemaker procedure he wanted to do an ablation for the A-Fib. about 1 month and a half ago he prescribed Eliquis for my procedure that was supposed to be April 9th but has been cancelled due to the COVID-19 issues. I have gained about 15-20 lbs since I started taking it, I am fatigued and my joints ache and hurt all the time, and I am having problems having regular bowel movements. I thought I was losing my mind to begin with until I looked at some of these reviews and saw others who were having the same kinds of issues. I am still on it and don't have any idea when I might be able to have the procedure and get off of it. I asked the nurse if the weight gain or constipation might be from Eliquis and she said no...???? Prayers for me would be appreciated!”

1 / 10
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lwlnng2wndvjqo1 · Taken for 1 to 6 months March 17, 2019

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “Have the god given good sense to question doctors and if the substance is doing all you say it is, get off it. Besides, from all I can determine, Eliquis doesn't directly address AFIB, only potential symptoms resulting from AFIB. This stuff ain't good for you and will only add additional complications making living absolutely miserable. I wonder just how much kick back is sent to doctors and pharmacies for recommending this stuff.”

1 / 10
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Daughter · Taken for less than 1 month May 22, 2019

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “My 88 year old father was prescribed the lowest dosage of Eliquis, which he took for 2 days before experiencing a catastrophic spontaneous brain bleed resulting in a coma. He died 4 days later. The death certificate listed the the cause of death as Acute Hemorrhagic Stroke as a consequence of anticoagulation with Apixaban (Eliquis). He was in excellent health. This should not have happened.”

1 / 10
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PeggyV April 19, 2020

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “Because of an irratic heart beat, my cardiologist put me on Eliquis 2.5mg twice a day. I have been on this med. For about 4 months. Mainly,I am having pain in my feet and redness, particularly when I get up in the morning. Also, I have pain in my left ankle, together with one of my toes. I have also notice pains in my arms and hands. I keep thinking it is arthritis. In addition, I feel out of balance when I walk, plus vision seems affected. I still function, but moderately. I also take Metoprolol, 12.5mg per day. Help....I am 81 years old.”

5 / 10
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SG · Taken for less than 1 month June 18, 2020

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “My sister was diagnosed with Atrial Fibrillation and was prescription Eliquis. After three weeks of constant head aches, which she reported to her doctor, they made her an appointment for a check up. Three days before her appointment she suffered a brain aneurysm and died. The doctor attending her said they had "reports" of this "common" problem. If you're prescribed a medication that makes you feel worse and your doctor doesn't respond immediately with a solution, go to someone who will respond. Check the warning on the medication website, it could save your life.”

1 / 10
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R.Wilson · Taken for 1 to 6 months January 29, 2019

Eliquis (apixaban) for Pulmonary Embolism: “I have been on Eliquis for pulmonary embolism in both lungs. I was a healthy, active 42 year old woman, and no reason for them. I had severe headaches, muscle weakness, and fatigue for a few weeks. I started feeling a lot better, and was doing well with my usual kick boxing workout, until recently. I am now experiencing, fatigue, and severe back pain, as well as dizziness, and shortness of breath. I'm hoping I can get off of the meds in March. Anyone else experience this?”

5 / 10
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Mary · Taken for 1 to 6 months May 18, 2020

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “I want to let people know there are alternatives to medication. Eliquis caused my husband to be very sick. He had atrial flutter. But try natural remedies to strengthen the heart like Hawthorn solid extract and coQ10. Speak to a herbalist natural may work for you. Pharma just wants to keep you on medications for the money they only treat the symptoms not the underlying condition which could be a mineral deficiency or something to strengthen the heart.. So please look in to alternatives not just pharmaceuticals”

1 / 10
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Joe · Taken for 1 to 2 years January 11, 2021

Eliquis (apixaban) for Pulmonary Embolism: “I have had 3 PE's over the last few years, the first 2 after an outpatient surgery and general anesthesia, then a 3rd small one after stopping eliquis. I have been taking eliquis and over time I have been experiencing increasingly terrible side effects, including chest tightness, shortness of breathe, GERD, muscle weakness, joint pain, weight gain while eating less and headaches. I am planning to go to aspirin. Has anyone gone from eliquis to aspirin successfully? Don't want another PE but can't live with these side effects.”

2 / 10
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PR · Taken for 1 to 6 months November 4, 2019

Eliquis (apixaban) for Pulmonary Embolism: “I wound up with PE and DVT behind right knee. I was in the hospital for 72 hours and was prescribed Eliquis twice a day. I feel like I have lost me..I am in constant leg pain, my joints and lower back hurt so bad. After two week my hair started falling out and I wound up with Edema. had sudden weight gain with no diet change. I get dizzy and light headed and fumble to speak at times. My body itches constantly .. I just want off this drug!! I feel it is poisoning me and the shortness of breath and wheezing is scaring me. Please don't take this drug....I struggle every day to walk and fight through the pain.”

4 / 10
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KittyKat K-K · Taken for less than 1 month April 17, 2019

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “Cardiologist prescribed Eliquis 3 weeks ago for occasional Afib, and was ugly to me when I said “that’s pretty strong to start out with”. I regret not discussing this with my primary care doctor because he agreed with me! Still, he wasn’t comfortable taking me off of it since he didn’t prescribe it. I was light headed the first week and for the last week I have been experiencing the worst joint pain and headache ever!! I told my husband I cannot and will not live like this!! I will be in the cardiologists office tomorrow for testing...I intend to find a way to get off this HORRIBLE “poison”!!!”

1 / 10
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dan · Taken for 1 to 6 months October 24, 2019

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “I was on Eliquis for three weeks prior to a cardioversion. Made me feel tired, fatigued, no motivation. I would get a headache in the afternoon and would wake up with a headache. I would sometimes feel woozy, almost dizzy. After cardioversion I went to 1/2 tablet for a week. Side effects somewhat less, but still terrible. I didn't feel like doing anything, dishes piled up in the sink, house didn't get swept, I just felt like sitting. I stopped and the next day felt great. Not doing this again.”

4 / 10
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Elise · Taken for 1 to 6 months March 20, 2019

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “My mom was put on Eliquis for a-fib, then after a month and a half she started bleeding rectally. We took her to the emergency room where they found that it was necessary to give her a blood transfusion. It took 2.5 days for the bleeding to stop. She was put in rehab, but after 11 days her blood pressure dropped dangerously low. She died a few days later and I feel that this entire event was a result of Eliquis. Older people should not be put on this drug!”

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NZnurse · Taken for 6 months to 1 year November 17, 2020

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “My Husband has been on Eliquis 5mg twice a day for several months after being on Plavix after a Coronary Stent in Dec 2019. The Cardiologist insisted since he has had Atrial Fib when ever he has a health crisis. So on the Plavix he had some nasty bruising when ever he had blood drawn. Now on the Eliquis he has swelling in his hands and arms. Worse is the swelling of face around the mouth and lips. He also loses his voice from pharyngeal swelling. His breathing is fine. It usually settles down after a few hrs but last time it took longer. We cut the Eliquis in half and reduced the dose but he has had the same reaction again. It happens after taking it in the evening and swelling comes up over night. Changing back to Aspirin to see if the Eliquis is the problem. He is also on Toprol or Metaprolol which he has also cut back on to 50mg once a day. His BP and pulse are fine. Age 74 and almost completely incapacitated by these drugs. Not sleeping, and loss of appetite also.”

2 / 10
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Anonymous · Taken for 1 to 6 months November 10, 2020

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “Mother had good health for 94 yr old, able to care for herself, socialize + enjoy with zest for life. She was put on this drug because of irregular heart rhythm. She went down in bathroom, was taken to ED, cat scanned with brain bleed. Came home, perked up to her old self but 10 days later, lost speech+self-care - new CAT scan reveals more bleed, now she's on hospice. Crazy. We believe drug has all to do with this because of her health status+ NO chronic conditions, none. This lady could stay up all day, drove her own car until 6 wks ago, ate 3 meals a day, went to church every Sunday. Carried a just-in-case cane, for balance.”

2 / 10
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Kass · Taken for 1 to 2 years September 6, 2019

Eliquis (apixaban) for Deep Vein Thrombosis: “I was put on Eliquis by my MD just because he liked it better than Warfarin. Was previously on Warfarin with no problems. On Eliquis I have experienced severe muscle spasms and weakness. Also very tired, eyes are blurry, nose bleeds, weight gain, itching, and just general malaise. I asked my Dr several times to take me off Eliquis and put me back on Warfarin. He refused. I changed Dr's, got off the Eliquis back and Warfarin. I now feel soooooo much better and muscles are getting stronger and I have my energy back. This Eliquis is poison to me. I also will note I had no A-Fib. Never did....Listen to your body. It knows best.”

5 / 10
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Phoebe June 2, 2020

Eliquis (apixaban) for Deep Vein Thrombosis: “I was prescribed Eliquis after experiencing an upper extremity deep vein thrombosis due to thoracic outlet syndrome. The clot was dissolved in hospital through thrombolysis. I was sent home with Eliquis 10 mgs. x2 per day for a week, then 5 mgs x2 per day for maintenance. I didn't realize how horrible this drug made me feel until I called my hematologist after 3 months and begged him to reduce the dose. I experienced extreme fatigue, depression/apathy, muscle pain all over my body, and joint pain that would keep me up at night in my hips and lower back. My whole body began to hurt all the time after about 5 weeks on the medication. I couldn't do any exercise without being unable to get out of a chair for days afterwards. Not to mention the horrible heartburn. Fortunately, I see a TOS expert soon, and fingers crossed will be able to drop the Eliquis entirely. Has been an awful experience.”

2 / 10
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Nick · Taken for less than 1 month December 20, 2020

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “My mother (75) was taken off Warfarin after 20 years, and prescribed Eliquis for convenience. Four days on Eliquis was more than enough, just got back from the ER where we spent the night getting her checked out. She experienced tremors, fatigue, nausea, loss of balance, and basically felt like rubbish! This drug seems quite dangerous, even though our cardiologist tells us she has successfully placed hundreds on the drug. I would not recommend it to anyone!!!”

1 / 10
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Maria · Taken for 1 to 6 months December 30, 2018

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “My father was put on this drug by his doctor 5 mg twice a day. Doctor said he had a fib which was news to him. But two weeks after he started or maybe three weeks he developed this crazy itching feeling all over his body, stabbing pains in his stomach, wheezing, and then it gave him some kind of an ulcerated ulcer in the stomach where his stool was black, took him to his doctor and they found blood in the stool. Also he was wheezing for a month took him for an x-ray and he was in the beginnings of pneumonia. Needless to say his regular doctor told him to get off of Eliquis. My dad walks for an hour on the treadmill and the past couple of weeks he noticed that his heart was starting to go fast and he would get out of breath very easily and that’s never happened before. Think twice before you start taking this drug.”

1 / 10
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Kodee · Taken for 1 to 6 months October 15, 2019

Eliquis (apixaban) for Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery: “I would like to know if anyone else on Eliquis has experienced the following while on this med. I have had a 12 pound weight gain in three months, a cough that won’t go away; gout, balance issues and serious joint pain. Am I the only one? are others experiencing some of the same. Every day I wake up my weight is up two more pounds. I am very tired all the time. Help I feel like I am going nuts and the doctors think I am a hypochondriac .”

6 / 10
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Haggy · Taken for less than 1 month May 24, 2019

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “Shortly after starting Eliquis I became short of breath and developed red itchy botches on my legs. Can hardly walk to the corner now. Feel unwell and lightheaded.Think I will look into getting off this horrible drug. Have no life anyway taking it. What else will this poison cause next. Calling FDA.”

1 / 10
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Lola July 30, 2020

Eliquis (apixaban) for Pulmonary Embolism: “Was placed on Eliquis after a small PE. The clot was dissolved within three weeks, so while I’m grateful the Eliquis did it’s job, I begged my doctor to take me off it and got switched to Warfarin. Eliquis just made me feel lifeless. I all day fatigue and weakness, feeling spacey and zoned out to the degree that it was very challenging to work at times, dizziness, heart palpitations, spells where I felt on the verge of passing out, difficulty swallowing, random weird pains in my eyes, ears, and extremities, back spasms and constant back pain, water weight gain and uncomfortable bloating and swelling, swollen feet and ankles, nausea, GI distress, stomach pains, and diarrhea, and rectal bleeding. Also had liver tests come back with abnormalities while on the med. These symptoms caused my doctor to refer me to several trips to the ER.”

3 / 10
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Delroy November 26, 2013

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “I have Atrial Fibrillation and thought I would try Eliquis due to its superior safety protocol. I have only been on it for 2 weeks but after the first several days, I have noticed an increasing burning/flushing sensation similar to a sun burn over most of my body. I have not had any gastrointestinal upset. I will continue to take Eliquis for a few more days but may have to discontinue it.”

5 / 10
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Totoro · Taken for 6 months to 1 year April 16, 2014

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “I have been taking Eliquis for eight months now. I have been in and out of atrial fibrillation, and have had no problems with Eliquis. None of the side effects have appeared for me. It is easy to use and a huge improvement over warfarin.”

10 / 10
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Dodee51 · Taken for less than 1 month December 19, 2020

Eliquis (apixaban) for Prevention of Thromboembolism in Atrial Fibrillation: “I was in Afib in the hospital this last time and they prescribed Eliquis. This is HORRIBLE medicine. I was only on it for 8 days and I got severe vertigo and I was so winded that I couldn't even walk to the kitchen without feeling like I was gonna faint. My appetite was almost non existent. I will NEVER take this medicine again. The side effects are brutal.”

1 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.