Zofran ODT Interactions
There are 360 drugs known to interact with Zofran ODT (ondansetron), along with 2 disease interactions. Of the total drug interactions, 127 are major, 227 are moderate, and 6 are minor.
- View all 360 medications that may interact with Zofran ODT
- View Zofran ODT disease interactions (2)
Most frequently checked interactions
View interaction reports for Zofran ODT (ondansetron) and the medicines listed below.
- albuterol
- baclofen
- Benadryl (diphenhydramine)
- clonazepam
- Cymbalta (duloxetine)
- famotidine
- Flexeril (cyclobenzaprine)
- gabapentin
- hydroxyzine
- ibuprofen
- levothyroxine
- Lyrica (pregabalin)
- melatonin
- Norco (acetaminophen / hydrocodone)
- omeprazole
- oxycodone
- pantoprazole
- Phenergan (promethazine)
- prednisone
- promethazine
- propranolol
- Protonix (pantoprazole)
- Singulair (montelukast)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zyrtec (cetirizine)
Zofran ODT disease interactions
There are 2 disease interactions with Zofran ODT (ondansetron) which include:
Report options
More about Zofran ODT (ondansetron)
- Zofran ODT consumer information
- Compare alternatives
- Reviews (61)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- Drug class: 5HT3 receptor antagonists
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Zofran
Zofran (ondansetron) is used to prevent nausea and vomiting caused by surgery or cancer medicines ...
Metoclopramide
Metoclopramide is used short-term to treat heartburn caused by gastroesophageal reflux. Learn about ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Meclizine
Meclizine is used to treat or prevent nausea, vomiting, and dizziness caused by motion sickness ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Promethazine
Promethazine is a phenothiazine and antihistamine used to treat allergies, motion sickness, nausea ...
Dexamethasone
Dexamethasone is used to treat inflammatory conditions such as allergies, skin conditions ...
Olanzapine
Olanzapine (brand name Zyprexa) is an atypical antipsychotic that may be used to treat adults and ...
Ativan
Ativan is a benzodiazepine used to treat anxiety disorders or anxiety associated with depression ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
