Nefazodone Drug Interactions
Currently displaying a list of 776 drugs known to interact with nefazodone.
- 266 major drug interactions
- 484 moderate drug interactions
- 26 minor drug interactions
Medications known to interact with nefazodone
Note: Showing generic names only.
5
A
- abametapir topical
- abemaciclib
- abiraterone
- acalabrutinib
- acebutolol
- acetazolamide
- acetylcarbromal
- acrivastine
- adagrasib
- ado-trastuzumab emtansine
- aldesleukin
- alfentanil
- alfuzosin
- aliskiren
- allopurinol
- almotriptan
- alosetron
- alprazolam
- alprostadil
- ambrisentan
- amifampridine
- amiloride
- amiodarone
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amprenavir
- amyl nitrite
- apixaban
- apomorphine
- apraclonidine ophthalmic
- aprepitant
- aripiprazole
- armodafinil
- asciminib
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atazanavir
- atenolol
- atogepant
- atorvastatin
- atrasentan
- avacopan
- avanafil
- avapritinib
- avatrombopag
- axitinib
- azatadine
- azilsartan medoxomil
- azithromycin
B
- baclofen
- bedaquiline
- belzutifan
- benazepril
- bendroflumethiazide
- benzgalantamine
- benzthiazide
- benztropine
- bepridil
- betamethasone
- betaxolol
- bexarotene
- binimetinib
- biperiden
- bisoprolol
- black cohosh
- bortezomib
- bosentan
- bosutinib
- brentuximab
- brexanolone
- brexpiprazole
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- budesonide
- budesonide nasal
- bumetanide
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabozantinib
- calaspargase pegol
- candesartan
- cannabidiol
- cannabis
- capecitabine
- capivasertib
- capmatinib
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carteolol
- carvedilol
- cenobamate
- ceritinib
- cerivastatin
- cetirizine
- cevimeline
- chlophedianol
- chloral hydrate
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorothiazide
- chlorotrianisene
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorthalidone
- chlorzoxazone
- ciclesonide
- ciclesonide nasal
- cilostazol
- cinacalcet
- cisapride
- citalopram
- clarithromycin
- clemastine
- clevidipine
- clindamycin
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- cobimetinib
- cocaine nasal
- cocaine topical
- codeine
- colchicine
- conivaptan
- conjugated estrogens
- conjugated estrogens topical
- copanlisib
- cortisone
- crizotinib
- cyclandelate
- cyclizine
- cyclobenzaprine
- cyclophosphamide
- cyclosporine
- cyproheptadine
D
- dabrafenib
- daclatasvir
- daclizumab
- dantrolene
- dapsone
- daridorexant
- darifenacin
- darolutamide
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- deflazacort
- delavirdine
- deserpidine
- desflurane
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexamethasone
- dexamethasone nasal
- dexamethasone ophthalmic
- dexbrompheniramine
- dexfenfluramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- diazoxide
- dichlorphenamide
- dienestrol topical
- diethylstilbestrol
- difelikefalin
- digitoxin
- digoxin
- dihydroergotamine
- diltiazem
- dimenhydrinate
- diphenhydramine
- disopyramide
- divalproex sodium
- docetaxel
- dofetilide
- dolasetron
- dolutegravir
- donepezil
- doravirine
- doxazosin
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxylamine
- dronabinol
- dronedarone
- droperidol
- drospirenone
- duloxetine
- dutasteride
- duvelisib
E
- echinacea
- efavirenz
- elacestrant
- elagolix
- eletriptan
- eliglustat
- eluxadoline
- enalapril
- enalaprilat
- encorafenib
- enflurane
- enfortumab vedotin
- entrectinib
- enzalutamide
- epirubicin
- eplerenone
- epoprostenol
- eprosartan
- eravacycline
- erdafitinib
- ergonovine
- ergotamine
- erlotinib
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- esmolol
- estazolam
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethacrynic acid
- ethanol
- ethaverine
- ethinyl estradiol
- ethosuximide
- ethotoin
- etomidate
- etonogestrel
- etoposide
- etranacogene dezaparvovec
- etrasimod
- etravirine
- evening primrose
- everolimus
- ezogabine
F
- fedratinib
- felbamate
- felodipine
- fenfluramine
- fenoldopam
- fentanyl
- fesoterodine
- fexinidazole
- fidanacogene elaparvovec
- finasteride
- finerenone
- flavoxate
- flibanserin
- fluconazole
- fludrocortisone
- flunisolide
- flunisolide nasal
- fluorometholone ophthalmic
- fluoxetine
- fluphenazine
- flurazepam
- fluticasone
- fluticasone nasal
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosinopril
- fostamatinib
- fostemsavir
- frovatriptan
- furazolidone
- furosemide
G
- gabapentin
- gabapentin enacarbil
- galantamine
- ganaxolone
- gefitinib
- gepirone
- gilteritinib
- ginkgo
- glasdegib
- glycerol phenylbutyrate
- granisetron
- grepafloxacin
- guanabenz
- guanadrel
- guanethidine
- guanfacine
H
- halazepam
- halofantrine
- haloperidol
- halothane
- heroin
- histamine phosphate
- hydralazine
- hydrochlorothiazide
- hydrocodone
- hydrocortisone
- hydroflumethiazide
- hydromorphone
- hydroxychloroquine
- hydroxyprogesterone
- hydroxyzine
I
- ibrexafungerp
- ibrutinib
- idarubicin
- idelalisib
- ifosfamide
- iloperidone
- iloprost
- imatinib
- imipramine
- inamrinone
- indacaterol
- indapamide
- indinavir
- infigratinib
- interferon beta-1a
- interferon beta-1b
- iobenguane I 123
- iohexol
- iomeprol
- iopamidol
- irbesartan
- irinotecan
- irinotecan liposomal
- isavuconazonium
- isocarboxazid
- isoflurane
- isoniazid
- isosorbide
- isosorbide dinitrate
- isosorbide mononitrate
- isoxsuprine
- isradipine
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivermectin
- ivosidenib
- ixabepilone
K
L
- labetalol
- lacosamide
- landiolol
- lansoprazole
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- leniolisib
- levamlodipine
- levetiracetam
- levobupivacaine
- levocetirizine
- levodopa
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levonorgestrel
- levorphanol
- lidocaine
- lindane topical
- linezolid
- lisinopril
- lithium
- lofexidine
- lomitapide
- lonafarnib
- lonapegsomatropin
- loperamide
- loratadine
- lorazepam
- lorcaserin
- lorlatinib
- losartan
- loteprednol ophthalmic
- lovastatin
- loxapine
- lumateperone
- lurasidone
- lurbinectedin
- lusutrombopag
M
- macitentan
- mannitol
- maprotiline
- maraviroc
- mavacamten
- mavorixafor
- mecamylamine
- medroxyprogesterone
- melatonin
- meloxicam
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methazolamide
- methocarbamol
- methohexital
- methotrexate
- methoxyflurane
- methsuximide
- methyclothiazide
- methyldopa
- methylene blue
- methylergonovine
- methylprednisolone
- methysergide maleate
- metoclopramide
- metolazone
- metoprolol
- metrizamide
- metyrosine
- mibefradil
- miconazole
- midazolam
- midostaurin
- mifepristone
- milnacipran
- milrinone
- minoxidil
- mipomersen
- mirabegron
- mirtazapine
- mirvetuximab soravtansine
- mitapivat
- mitotane
- mitoxantrone
- mobocertinib
- modafinil
- moexipril
- molindone
- mometasone
- mometasone nasal
- morphine
- morphine liposomal
N
- nabilone
- nadolol
- nalbuphine
- naldemedine
- naloxegol
- naltrexone
- naratriptan
- nebivolol
- nelfinavir
- neratinib
- nesiritide
- nevirapine
- nicardipine
- nifedipine
- nilotinib
- nimodipine
- nirogacestat
- nisoldipine
- nitisinone
- nitroglycerin
- nitroprusside
- nitrous oxide
- norethindrone
- norgestrel
- nortriptyline
O
- olanzapine
- olaparib
- oliceridine
- olmesartan
- olopatadine nasal
- olutasidenib
- omaveloxolone
- ondansetron
- opicapone
- opium
- oritavancin
- orphenadrine
- osilodrostat
- osimertinib
- ospemifene
- oxcarbazepine
- oxycodone
- oxymorphone
- ozanimod
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- paliperidone
- palonosetron
- palovarotene
- panobinostat
- papaverine
- paraldehyde
- paramethadione
- paricalcitol
- paroxetine
- pazopanib
- pegaspargase
- peginterferon beta-1a
- pemigatinib
- penbutolol
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perindopril
- perphenazine
- pexidartinib
- phenacemide
- phenelzine
- phenobarbital
- phenoxybenzamine
- phensuximide
- phentolamine
- pimavanserin
- pimecrolimus topical
- pimozide
- pindolol
- pioglitazone
- pirtobrutinib
- pitolisant
- polatuzumab vedotin
- polyethylene glycol 3350 with electrolytes
- polythiazide
- pomalidomide
- ponatinib
- posaconazole
- pralsetinib
- pravastatin
- prazosin
- prednisolone
- prednisolone ophthalmic
- prednisone
- pregabalin
- primidone
- procarbazine
- prochlorperazine
- procyclidine
- progesterone
- promazine
- promethazine
- propafenone
- propiomazine
- propoxyphene
- propranolol
- protriptyline
- pyrilamine
Q
R
- ramelteon
- ramipril
- ranolazine
- rasagiline
- rauwolfia serpentina
- red yeast rice
- regorafenib
- remdesivir
- remifentanil
- remimazolam
- repaglinide
- repotrectinib
- reserpine
- retapamulin topical
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilpivirine
- rimegepant
- riociguat
- ripretinib
- risperidone
- ritlecitinib
- ritonavir
- rivaroxaban
- rizatriptan
- roflumilast topical
- romidepsin
- ropinirole
- ropivacaine
- rotigotine
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- safinamide
- salmeterol
- saquinavir
- saxagliptin
- scopolamine
- secobarbital
- seladelpar
- selegiline
- selpercatinib
- selumetinib
- sertraline
- sevoflurane
- sibutramine
- sildenafil
- silodosin
- simeprevir
- simvastatin
- siponimod
- sirolimus
- sirolimus protein-bound
- sirolimus topical
- sodium oxybate
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sonidegib
- sotalol
- sotorasib
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- sufentanil
- sumatriptan
- sunitinib
- suvorexant
- suzetrigine
T
- tacrolimus
- tadalafil
- tamoxifen
- tamsulosin
- tapentadol
- tasimelteon
- tazemetostat
- tecovirimat
- tedizolid
- telithromycin
- telmisartan
- telotristat
- temazepam
- temsirolimus
- tepotinib
- terazosin
- terfenadine
- teriflunomide
- testosterone
- testosterone topical
- tetrabenazine
- thalidomide
- theophylline
- thioguanine
- thioridazine
- thiotepa
- thiothixene
- tiagabine
- ticagrelor
- timolol
- tisotumab vedotin
- tizanidine
- tofacitinib
- tolazoline
- tolterodine
- tolvaptan
- toremifene
- torsemide
- trabectedin
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- treosulfan
- treprostinil
- tretinoin
- triamcinolone
- triamcinolone nasal
- triamcinolone ophthalmic
- triamterene
- triazolam
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethaphan camsylate
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- trofinetide
- troglitazone
- troleandomycin
- tryptophan
- tucatinib
U
V
- vadadustat
- valbenazine
- valdecoxib
- valerian
- valoctocogene roxaparvovec
- valproic acid
- valsartan
- vamorolone
- vardenafil
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vibegron
- vigabatrin
- vilazodone
- vinblastine
- vincristine
- vincristine liposome
- vinorelbine
- voclosporin
- vorapaxar
- vorasidenib
- voriconazole
- vortioxetine
- voxelotor
Y
Z
- zafirlukast
- zaleplon
- zanubrutinib
- zavegepant
- ziconotide
- zileuton
- ziprasidone
- zolmitriptan
- zolpidem
- zonisamide
- zuranolone
Nefazodone alcohol/food interactions
There is 1 alcohol/food interaction with nefazodone.
Nefazodone disease interactions
There are 6 disease interactions with nefazodone which include:
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- Drug class: phenylpiperazine antidepressants
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
