Symproic Drug Interactions
Currently displaying a list of 180 drugs known to interact with Symproic (naldemedine).
- 12 major drug interactions
- 165 moderate drug interactions
- 3 minor drug interactions
Medications known to interact with Symproic
Note: Showing generic names only.
- abametapir topical
- abrocitinib
- adagrasib
- alpelisib
- alvimopan
- amiodarone
- amprenavir
- apalutamide
- aprepitant
- armodafinil
- asciminib
- atazanavir
- avacopan
- azithromycin
- cabozantinib
- capivasertib
- capmatinib
- captopril
- carbamazepine
- carvedilol
- cenobamate
- ceritinib
- chloramphenicol
- ciprofloxacin
- clarithromycin
- clotrimazole
- cobicistat
- conivaptan
- crizotinib
- cyclosporine
- dabrafenib
- daclatasvir
- danicopan
- daridorexant
- darunavir
- delavirdine
- dexamethasone
- diltiazem
- dronedarone
- duvelisib
- echinacea
- efavirenz
- elacestrant
- elagolix
- eliglustat
- encorafenib
- enzalutamide
- erdafitinib
- erythromycin
- etravirine
- ezogabine
- fedratinib
- felodipine
- fenfluramine
- fexinidazole
- fidaxomicin
- flibanserin
- fluconazole
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- futibatinib
- lapatinib
- larotrectinib
- lasmiditan
- lazertinib
- lefamulin
- lenacapavir
- letermovir
- levacetylleucine
- levoketoconazole
- lomitapide
- lonafarnib
- lonapegsomatropin
- lorlatinib
- maribavir
- mavorixafor
- methylnaltrexone
- mibefradil
- miconazole
- mifepristone
- mitotane
- mobocertinib
- modafinil
- nafcillin
- nalmefene
- naloxegol
- naloxone
- naltrexone
- nefazodone
- nelfinavir
- neratinib
- nevirapine
- nifedipine
- nilotinib
- pacritinib
- pemigatinib
- pexidartinib
- phenobarbital
- phenytoin
- pirtobrutinib
- pitolisant
- ponatinib
- posaconazole
- pralsetinib
- pretomanid
- primidone
- ranolazine
- remdesivir
- repotrectinib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- ripretinib
- ritlecitinib
- ritonavir
- rolapitant
- rucaparib
- saquinavir
- sarecycline
- selpercatinib
- simeprevir
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotorasib
- spironolactone
- st. john's wort
- stiripentol
- suvorexant
- suzetrigine
- tacrolimus
- telaprevir
- telithromycin
- telotristat
- tepotinib
- ticagrelor
- tolvaptan
- treosulfan
- trofinetide
- troglitazone
- troleandomycin
- tucatinib
- vadadustat
- valbenazine
- vemurafenib
- venetoclax
- verapamil
- vimseltinib
- vorasidenib
- voriconazole
- voxelotor
Symproic alcohol/food interactions
There is 1 alcohol/food interaction with Symproic (naldemedine).
Symproic disease interactions
There are 3 disease interactions with Symproic (naldemedine) which include:
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- FDA approval history
- Drug class: peripheral opioid receptor antagonists
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
