Otrexup Interactions
There are 726 drugs known to interact with Otrexup (methotrexate), along with 5 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 145 are major, 566 are moderate, and 15 are minor.
- View all 726 medications that may interact with Otrexup
- View Otrexup alcohol/food interactions (3)
- View Otrexup disease interactions (5)
Most frequently checked interactions
View interaction reports for Otrexup (methotrexate) and the medicines listed below.
- amoxicillin
- amoxicillin
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- doxycycline
- doxycycline
- Enbrel (etanercept)
- Enbrel (etanercept)
- folic acid
- folic acid
- gabapentin
- gabapentin
- Humira (adalimumab)
- Humira (adalimumab)
- Lexapro (escitalopram)
- Lexapro (escitalopram)
- omeprazole
- omeprazole
- Orencia (abatacept)
- Orencia (abatacept)
- Plaquenil (hydroxychloroquine)
- Plaquenil (hydroxychloroquine)
- prednisone
- prednisone
- tizanidine
- tizanidine
- tramadol
- tramadol
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
Otrexup alcohol/food interactions
There are 3 alcohol/food interactions with Otrexup (methotrexate).
Otrexup disease interactions
There are 5 disease interactions with Otrexup (methotrexate) which include:
Report options
More about Otrexup (methotrexate)
- Otrexup consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (2)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: antimetabolites
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.