Skelaxin Drug Interactions
Currently displaying a list of 317 drugs known to interact with Skelaxin (metaxalone).
- 35 major drug interactions
- 282 moderate drug interactions
Medications known to interact with Skelaxin
Note: Showing generic names only.
- abobotulinumtoxinA
- acebutolol
- acetylcarbromal
- acrivastine
- aldesleukin
- alfentanil
- alfuzosin
- allopurinol
- alprazolam
- amitriptyline
- amobarbital
- amoxapine
- apomorphine
- apraclonidine ophthalmic
- aprocitentan
- aripiprazole
- asenapine
- ashwaganda
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- atenolol
- azatadine
- azilsartan medoxomil
- baclofen
- bedaquiline
- benztropine
- bepridil
- betaxolol
- biperiden
- bisoprolol
- black cohosh
- brentuximab
- brexanolone
- brexpiprazole
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromocriptine
- brompheniramine
- buprenorphine
- buspirone
- butabarbital
- butalbital
- butorphanol
- calaspargase pegol
- cannabidiol
- cannabis
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carteolol
- carvedilol
- cenobamate
- cetirizine
- chlophedianol
- chloral hydrate
- chlordiazepoxide
- chlormezanone
- chlorpheniramine
- chlorpromazine
- chlorthalidone
- citalopram
- clemastine
- clevidipine
- clobazam
- clofarabine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- codeine
- cyclizine
- cyproheptadine
- daclizumab
- dantrolene
- daridorexant
- daxibotulinumtoxinA
- deserpidine
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- difelikefalin
- dimenhydrinate
- diphenhydramine
- divalproex sodium
- doxazosin
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- droperidol
- duloxetine
- efavirenz
- entacapone
- eplerenone
- escitalopram
- esketamine
- eslicarbazepine
- esmolol
- estazolam
- eszopiclone
- ethacrynic acid
- ethanol
- ethosuximide
- ethotoin
- etranacogene dezaparvovec
- ezogabine
- felbamate
- fenfluramine
- fentanyl
- fidanacogene elaparvovec
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- idelalisib
- ifosfamide
- iloperidone
- imipramine
- incobotulinumtoxinA
- interferon beta-1a
- interferon beta-1b
- isocarboxazid
- isoniazid
- labetalol
- lamotrigine
- landiolol
- lasmiditan
- leflunomide
- lemborexant
- letibotulinumtoxinA
- levetiracetam
- levocetirizine
- levodopa
- levoketoconazole
- levomethadyl acetate
- levorphanol
- lidocaine
- lithium
- lofexidine
- lomitapide
- lorazepam
- loxapine
- lumateperone
- lurasidone
- maprotiline
- melatonin
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- methadone
- methocarbamol
- methohexital
- methotrexate
- methsuximide
- methyclothiazide
- metoclopramide
- metoprolol
- metyrosine
- mibefradil
- midazolam
- mipomersen
- mirtazapine
- mitotane
- molindone
- morphine
- morphine liposomal
- olanzapine
- oliceridine
- olopatadine nasal
- onabotulinumtoxinA
- opicapone
- opium
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- paliperidone
- papaverine
- paraldehyde
- paramethadione
- paroxetine
- pegaspargase
- peginterferon beta-1a
- penbutolol
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perphenazine
- pexidartinib
- phenacemide
- phenelzine
- phenobarbital
- phensuximide
- phentolamine
- phenytoin
- pimozide
- pindolol
- prabotulinumtoxinA
- pramipexole
- pregabalin
- primidone
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propiomazine
- propoxyphene
- propranolol
- protriptyline
- pyrilamine
- ramelteon
- rasagiline
- rauwolfia serpentina
- remdesivir
- remifentanil
- remimazolam
- reserpine
- rifampin
- rimabotulinumtoxinB
- risperidone
- ropinirole
- rotigotine
- rufinamide
- safinamide
- scopolamine
- secobarbital
- selegiline
- sertraline
- sibutramine
- silodosin
- sodium oxybate
- sotalol
- st. john's wort
- stiripentol
- sufentanil
- suvorexant
- tamsulosin
- tapentadol
- tasimelteon
- telmisartan
- temazepam
- teriflunomide
- tetrabenazine
- thalidomide
- thioguanine
- thiopental
- thioridazine
- thiothixene
- tiagabine
- tizanidine
- tolcapone
- topiramate
- trabectedin
- tramadol
- tranylcypromine
- trazodone
- triazolam
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
Skelaxin alcohol/food interactions
There is 1 alcohol/food interaction with Skelaxin (metaxalone).
Skelaxin disease interactions
There are 3 disease interactions with Skelaxin (metaxalone) which include:
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- Drug class: skeletal muscle relaxants
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Zanaflex
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Soma
Soma (carisoprodol) is used treat injuries and other painful muscle conditions. Includes Soma side ...
Diazepam
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Tizanidine
Tizanidine is a short-acting muscle relaxant and is used to treat spasticity. Learn about side ...
Baclofen
Baclofen is a muscle relaxant used to treat spasticity and muscle pain in conditions like multiple ...
Methocarbamol
Methocarbamol is a muscle relaxant that works by blocking pain sensations. Includes methocarbamol ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
