Estradiol/norethindrone/relugolix Drug Interactions
Currently displaying a list of 661 drugs known to interact with estradiol / norethindrone / relugolix.
- 180 major drug interactions
- 463 moderate drug interactions
- 18 minor drug interactions
Medications known to interact with estradiol/norethindrone/relugolix
Note: Showing generic names only.
A
- abametapir topical
- abrocitinib
- acarbose
- acetohexamide
- acitretin
- adagrasib
- adalimumab
- adenosine
- albiglutide
- albuterol
- alefacept
- alfuzosin
- alogliptin
- alosetron
- alpelisib
- amikacin
- amikacin liposome
- aminoglutethimide
- aminophylline
- amiodarone
- amisulpride
- amitriptyline
- amobarbital
- amoxapine
- amoxicillin
- ampicillin
- amprenavir
- anagrelide
- anakinra
- anastrozole
- anisindione
- apalutamide
- apomorphine
- aprepitant
- arformoterol
- aripiprazole
- armodafinil
- arsenic trioxide
- asciminib
- ascorbic acid
- asenapine
- asparaginase erwinia chrysanthemi
- asparaginase escherichia coli
- astemizole
- atazanavir
- atomoxetine
- atorvastatin
- avacopan
- azithromycin
- aztreonam
B
- bacampicillin
- bacitracin
- baricitinib
- bedaquiline
- belzutifan
- bendamustine
- benzgalantamine
- bepridil
- berotralstat
- betamethasone
- bexagliflozin
- bexarotene
- bimekizumab
- bisacodyl
- bitolterol
- boceprevir
- bosentan
- bosutinib
- brigatinib
- brivaracetam
- brodalumab
- budesonide
- buprenorphine
- bupropion
- butabarbital
- butalbital
C
- C1 esterase inhibitor (human)
- cabozantinib
- calaspargase pegol
- calcipotriene topical
- calcitriol topical
- canagliflozin
- canakinumab
- cannabidiol
- capmatinib
- carbamazepine
- carbenicillin
- carfilzomib
- carvedilol
- casanthranol
- cascara sagrada
- castor oil
- cefaclor
- cefadroxil
- cefamandole
- cefazolin
- cefditoren
- cefepime
- cefiderocol
- cefixime
- cefmetazole
- cefonicid
- cefoperazone
- cefotaxime
- cefotetan
- cefoxitin
- cefpodoxime
- cefprozil
- ceftaroline
- ceftazidime
- ceftibuten
- ceftizoxime
- ceftobiprole medocaril
- ceftriaxone
- cefuroxime
- cenobamate
- cephalexin
- cephalothin
- cephapirin
- cephradine
- ceritinib
- chenodiol
- chloramphenicol
- chloroquine
- chlorpromazine
- chlorpropamide
- cholestyramine
- cilostazol
- cimetidine
- cinoxacin
- ciprofloxacin
- cisapride
- citalopram
- cladribine
- clarithromycin
- clindamycin
- clobazam
- clofazimine
- clomipramine
- clotrimazole
- cloxacillin
- clozapine
- cobicistat
- colesevelam
- colestipol
- colistimethate
- conestat alfa
- conivaptan
- corticorelin
- corticotropin
- cortisone
- cosyntropin
- crizotinib
- cyclosporine
D
- dabigatran
- dabrafenib
- daclatasvir
- dalbavancin
- danicopan
- dantrolene
- dapagliflozin
- daptomycin
- daridorexant
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- deflazacort
- dehydroepiandrosterone
- delafloxacin
- delavirdine
- demeclocycline
- desipramine
- deutetrabenazine
- dexamethasone
- dicloxacillin
- dicumarol
- digoxin
- diltiazem
- dirithromycin
- disopyramide
- divalproex sodium
- dofetilide
- dolasetron
- donepezil
- doripenem
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxycycline
- dronedarone
- droperidol
- dulaglutide
- duloxetine
- duvelisib
E
- echinacea
- efavirenz
- elacestrant
- elafibranor
- elagolix
- eliglustat
- emapalumab
- empagliflozin
- enasidenib
- encorafenib
- enoxacin
- entrectinib
- enzalutamide
- epirubicin
- eravacycline
- eribulin
- ertapenem
- ertugliflozin
- erythromycin
- escitalopram
- eslicarbazepine
- ethanol
- ethinyl estradiol
- etrasimod
- etravirine
- etretinate
- exemestane
- exenatide
- ezogabine
F
- famotidine
- fedratinib
- felbamate
- fenfluramine
- fentanyl
- fexinidazole
- fexofenadine
- fezolinetant
- fidaxomicin
- fingolimod
- fitusiran
- flecainide
- flibanserin
- flotufolastat F 18
- fluconazole
- fludrocortisone
- fluoxetine
- fluphenazine
- fluvoxamine
- formoterol
- fosamprenavir
- fosaprepitant
- foscarnet
- fosphenytoin
- fostamatinib
- fostemsavir
- frovatriptan
- furazolidone
- futibatinib
G
- galantamine
- gallium Ga 68 gozetotide
- gallium ga 68 psma-11
- gatifloxacin
- gemifloxacin
- gentamicin
- gepirone
- gilteritinib
- givinostat
- glasdegib
- glimepiride
- glipizide
- glyburide
- glycerin
- glycerol phenylbutyrate
- golimumab
- granisetron
- grepafloxacin
- griseofulvin
- guselkumab
H
- halofantrine
- haloperidol
- halothane
- hemin
- hyaluronidase
- hydrocortisone
- hydroxychloroquine
- hydroxyzine
I
- ibrutinib
- ibutilide
- idarubicin
- iloperidone
- imatinib
- imipramine
- indacaterol
- indinavir
- infliximab
- inotuzumab ozogamicin
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iptacopan
- isavuconazonium
- isoetharine
- isoniazid
- isoproterenol
- isotretinoin
- istradefylline
- itraconazole
- ivabradine
- ivacaftor
- ivosidenib
K
L
- lactitol
- lactulose
- lamotrigine
- lapatinib
- larotrectinib
- lasmiditan
- lefamulin
- lemborexant
- lenacapavir
- lenalidomide
- lenvatinib
- lesinurad
- letermovir
- letrozole
- levacetylleucine
- levalbuterol
- levobupivacaine
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levothyroxine
- levothyroxine / liothyronine
- lidocaine
- linaclotide
- linagliptin
- lincomycin
- linezolid
- liothyronine
- liotrix
- liraglutide
- lisdexamfetamine
- lithium
- lixisenatide
- lofexidine
- lomefloxacin
- lomitapide
- lonafarnib
- lonapegsomatropin
- loperamide
- loracarbef
- lorlatinib
M
- macimorelin
- magnesium citrate
- magnesium hydroxide
- maprotiline
- mavacamten
- mavorixafor
- mefloquine
- melatonin
- mephobarbital
- meropenem
- mesoridazine
- metaproterenol
- metformin
- methadone
- methicillin
- methotrimeprazine
- methylprednisolone
- metreleptin
- metronidazole
- metyrapone
- mezlocillin
- mibefradil
- miconazole
- midostaurin
- mifepristone
- miglitol
- miltefosine
- mineral oil
- minocycline
- mirtazapine
- mitapivat
- mitotane
- mobocertinib
- modafinil
- momelotinib
- morphine
- morphine liposomal
- moxifloxacin
- mycophenolate mofetil
- mycophenolic acid
N
- nafcillin
- nalidixic acid
- naratriptan
- nateglinide
- nefazodone
- nelfinavir
- nemolizumab
- neomycin
- neratinib
- netilmicin
- nevirapine
- nicotine
- nilotinib
- nitrofurantoin
- norfloxacin
- nortriptyline
- novobiocin
O
- odevixibat
- ofloxacin
- olanzapine
- olaparib
- oliceridine
- olodaterol
- olutasidenib
- omadacycline
- omaveloxolone
- ondansetron
- oritavancin
- osilodrostat
- osimertinib
- ospemifene
- oxacillin
- oxaliplatin
- oxcarbazepine
- oxtriphylline
- oxytetracycline
- oxytocin
- ozanimod
P
- pacritinib
- paliperidone
- palonosetron
- panobinostat
- papaverine
- paromomycin
- pasireotide
- pazopanib
- pegaspargase
- pemigatinib
- penicillin g benzathine
- penicillin g potassium
- penicillin g sodium
- penicillin v potassium
- pentamidine
- pentobarbital
- perampanel
- perflutren
- perphenazine
- pexidartinib
- phenobarbital
- phenolphthalein
- phenylbutazone
- phenytoin
- piflufolastat F 18
- pimavanserin
- pimozide
- pioglitazone
- piperacillin
- pirbuterol
- pirfenidone
- pirtobrutinib
- pitolisant
- pivmecillinam
- plazomicin
- polyethylene glycol 3350
- polyethylene glycol 3350 with electrolytes
- polymyxin b
- pomalidomide
- ponatinib
- ponesimod
- posaconazole
- pralsetinib
- pramlintide
- prednisolone
- prednisone
- pretomanid
- primaquine
- primidone
- probucol
- procainamide
- procaine penicillin
- prochlorperazine
- promazine
- promethazine
- propafenone
- propofol
- propoxyphene
- protriptyline
- prucalopride
Q
R
- raloxifene
- ramelteon
- ranolazine
- rasagiline
- repaglinide
- repotrectinib
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rilonacept
- rilpivirine
- ripretinib
- risperidone
- ritlecitinib
- ritodrine
- ritonavir
- rivastigmine
- roflumilast
- rolapitant
- romidepsin
- ropinirole
- rosiglitazone
- rosuvastatin
- rucaparib
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- salmeterol
- saquinavir
- sarecycline
- sarilumab
- satralizumab
- saw palmetto
- saxagliptin
- secobarbital
- secukinumab
- selegiline
- selpercatinib
- selumetinib
- semaglutide
- senna
- sertraline
- sevoflurane
- siltuximab
- simeprevir
- siponimod
- sirolimus
- sitagliptin
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sorafenib
- sotagliflozin
- sotalol
- sotorasib
- sparfloxacin
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- streptomycin
- succinylcholine
- sugammadex
- sulfadiazine
- sulfadoxine
- sulfamethizole
- sulfamethoxazole
- sulfasalazine
- sulfinpyrazone
- sulfisoxazole
- sunitinib
- suvorexant
- suzetrigine
T
- tacrine
- tacrolimus
- tamoxifen
- tasimelteon
- tazemetostat
- tebentafusp
- tecovirimat
- tedizolid
- telaprevir
- telavancin
- telithromycin
- telotristat
- temsirolimus
- tepotinib
- terbutaline
- terfenadine
- teriflunomide
- testolactone
- tetrabenazine
- tetracycline
- thalidomide
- theophylline
- thioridazine
- thyroid desiccated
- ticagrelor
- ticarcillin
- tigecycline
- tinidazole
- tipranavir
- tirzepatide
- tivozanib
- tizanidine
- tobramycin
- tocilizumab
- tofacitinib
- tolazamide
- tolbutamide
- tolvaptan
- topiramate
- toremifene
- tovorafenib
- tramadol
- tranexamic acid
- trazodone
- triamcinolone
- triamcinolone ophthalmic
- triclabendazole
- trifluoperazine
- triflupromazine
- trimeprazine
- trimipramine
- trofinetide
- troglitazone
- troleandomycin
- trovafloxacin
- tucatinib
U
V
- vadadustat
- valbenazine
- valproic acid
- vamorolone
- vancomycin
- vandetanib
- vardenafil
- varenicline
- vasopressin
- vemurafenib
- venetoclax
- venlafaxine
- verapamil
- vimseltinib
- voclosporin
- vorasidenib
- voriconazole
- voxelotor
W
Z
Estradiol/norethindrone/relugolix alcohol/food interactions
There are 9 alcohol/food interactions with estradiol / norethindrone / relugolix.
Estradiol/norethindrone/relugolix disease interactions
There are 24 disease interactions with estradiol / norethindrone / relugolix which include:
- abnormal genital bleeding
- abnormal vaginal bleeding
- carcinomas (estrogenic)
- hypercalcemia in breast cancer
- hypertension
- thromboembolism/cardiovascular
- hepatic neoplasms
- breast malignancy
- liver disease
- thromboembolism
- angioedema
- gallbladder disease
- hypercalcemia
- hyperlipidemia
- liver disease
- melasma
- depression
- fluid retention
- glucose intolerance
- retinal thrombosis
- thyroid function tests
- QT prolongation
- hyperlipidemia
- weight gain
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- estradiol/norethindrone/relugolix consumer information
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- Drug class: sex hormone combinations
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
