Orilissa Drug Interactions
Currently displaying a list of 373 drugs known to interact with Orilissa (elagolix).
- 52 major drug interactions
- 303 moderate drug interactions
- 18 minor drug interactions
Medications known to interact with Orilissa
Note: Showing generic names only.
A
- abemaciclib
- abiraterone
- acalabrutinib
- afatinib
- alfentanil
- aliskiren
- alpelisib
- ambrisentan
- aminoglutethimide
- amobarbital
- amprenavir
- apalutamide
- apixaban
- apremilast
- aprepitant
- aripiprazole
- armodafinil
- artesunate
- atazanavir
- atogepant
- atorvastatin
- avacopan
- avanafil
- avapritinib
- axitinib
B
- bedaquiline
- belumosudil
- berotralstat
- betrixaban
- bexarotene
- bicalutamide
- binimetinib
- black cohosh
- boceprevir
- bortezomib
- bosentan
- bosutinib
- brentuximab
- brexpiprazole
- brigatinib
- bromocriptine
- budesonide
- buprenorphine
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabazitaxel
- cabozantinib
- cannabidiol
- capivasertib
- capmatinib
- carbamazepine
- cariprazine
- caspofungin
- cenobamate
- ceritinib
- cevimeline
- chloramphenicol
- chlorotrianisene
- cimetidine
- ciprofloxacin
- clarithromycin
- clofarabine
- clotrimazole
- cobicistat
- cobimetinib
- colchicine
- conivaptan
- conjugated estrogens
- conjugated estrogens topical
- copanlisib
- crinecerfont
- crizotinib
- cyclosporine
D
- dabigatran
- dabrafenib
- daclizumab
- danazol
- danicopan
- dapsone topical
- daridorexant
- darifenacin
- darolutamide
- darunavir
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- dehydroepiandrosterone
- delafloxacin
- delavirdine
- dexamethasone
- dienestrol topical
- diethylstilbestrol
- digoxin
- dihydroergotamine
- diltiazem
- docetaxel
- dolutegravir
- donepezil
- doravirine
- doxorubicin
- doxorubicin liposomal
- dronedarone
- drospirenone
- duvelisib
E
- edoxaban
- efavirenz
- elacestrant
- eliglustat
- elvitegravir
- empagliflozin
- encorafenib
- enfortumab vedotin
- entrectinib
- enzalutamide
- epirubicin
- ergonovine
- ergotamine
- erlotinib
- eslicarbazepine
- esterified estrogens
- estradiol
- estradiol topical
- estrone
- estropipate
- estropipate topical
- eszopiclone
- ethinyl estradiol
- etonogestrel
- etoposide
- etravirine
- everolimus
- exemestane
F
- fedratinib
- felbamate
- fenfluramine
- fentanyl
- fesoterodine
- fexofenadine
- fidaxomicin
- finerenone
- flibanserin
- fosamprenavir
- fosaprepitant
- fosphenytoin
- fostamatinib
- fostemsavir
G
- ganaxolone
- gefitinib
- gemfibrozil
- gepirone
- gilteritinib
- glasdegib
- glycerol phenylbutyrate
- griseofulvin
- guanfacine
H
I
- ibrutinib
- idarubicin
- idelalisib
- imatinib
- indacaterol
- indinavir
- infigratinib
- interferon beta-1a
- interferon beta-1b
- irinotecan
- irinotecan liposomal
- isavuconazonium
- itraconazole
- ivabradine
- ivacaftor
- ivosidenib
- ixabepilone
- ixazomib
K
L
- lapatinib
- larotrectinib
- lazertinib
- lefamulin
- leflunomide
- lemborexant
- lenacapavir
- lenalidomide
- leniolisib
- lesinurad
- levacetylleucine
- levobupivacaine
- levoketoconazole
- levomethadyl acetate
- levonorgestrel
- lidocaine
- linagliptin
- lomitapide
- lonafarnib
- lonapegsomatropin
- loperamide
- lorlatinib
- lumateperone
- lurasidone
- lusutrombopag
M
- macimorelin
- macitentan
- maraviroc
- maribavir
- mavacamten
- mavorixafor
- medroxyprogesterone
- mefloquine
- megestrol
- mephobarbital
- methadone
- methotrexate
- methylergonovine
- methysergide maleate
- metreleptin
- mibefradil
- midostaurin
- mifepristone
- mipomersen
- mirabegron
- mirtazapine
- mitotane
- mitoxantrone
- mobocertinib
- modafinil
- montelukast
- morphine
N
- nafcillin
- naldemedine
- naloxegol
- naltrexone
- nefazodone
- nelfinavir
- nevirapine
- nilotinib
- niraparib
- nirogacestat
- nitisinone
- norethindrone
- norgestrel
O
- olaparib
- oliceridine
- olutasidenib
- omaveloxolone
- oritavancin
- osilodrostat
- osimertinib
- oxcarbazepine
- oxycodone
P
- paclitaxel
- paclitaxel protein-bound
- pacritinib
- palbociclib
- palovarotene
- panobinostat
- pazopanib
- peginterferon beta-1a
- pemigatinib
- pentobarbital
- perampanel
- pexidartinib
- phenobarbital
- phenylbutazone
- phenytoin
- pimavanserin
- pirtobrutinib
- ponatinib
- posaconazole
- pralsetinib
- praziquantel
- pretomanid
- primidone
- progesterone
- progesterone topical
- prucalopride
Q
R
- ramelteon
- relugolix
- remdesivir
- repaglinide
- repotrectinib
- revumenib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- rifaximin
- rilpivirine
- rimegepant
- riociguat
- ripretinib
- ritlecitinib
- ritonavir
- rivaroxaban
- rolapitant
- rufinamide
- ruxolitinib
- ruxolitinib topical
S
- saquinavir
- saxagliptin
- secobarbital
- selpercatinib
- selumetinib
- sirolimus
- sirolimus protein-bound
- solifenacin
- somapacitan-beco
- somatrem
- somatrogon
- somatropin
- sonidegib
- sorafenib
- sotorasib
- sparsentan
- st. john's wort
- stiripentol
- sufentanil
- sulfinpyrazone
- sunitinib
- suvorexant
- suzetrigine
T
- tacrolimus
- tadalafil
- talazoparib
- tamoxifen
- tasimelteon
- tazemetostat
- telaprevir
- telithromycin
- telotristat
- temsirolimus
- tenofovir alafenamide
- tenofovir disoproxil
- tepotinib
- teriflunomide
- thioguanine
- thiotepa
- ticagrelor
- tipranavir
- tofacitinib
- tolvaptan
- topotecan
- toremifene
- tovorafenib
- trabectedin
- tramadol
- trametinib
- troglitazone
- troleandomycin
- tucatinib
U
V
Z
Orilissa disease interactions
There are 3 disease interactions with Orilissa (elagolix) which include:
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
