Aleve PM Interactions
There are 797 drugs known to interact with Aleve PM (diphenhydramine/naproxen), along with 19 disease interactions, and 4 alcohol/food interactions. Of the total drug interactions, 114 are major, 662 are moderate, and 21 are minor.
- View all 797 medications that may interact with Aleve PM
- View Aleve PM alcohol/food interactions (4)
- View Aleve PM disease interactions (19)
Most frequently checked interactions
View interaction reports for Aleve PM (diphenhydramine / naproxen) and the medicines listed below.
- Aleve (naproxen)
- amlodipine
- aspirin
- atorvastatin
- Benadryl (diphenhydramine)
- benzonatate
- CoQ10 (ubiquinone)
- cyclobenzaprine
- diclofenac
- famotidine
- gabapentin
- hydrochlorothiazide
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- melatonin
- meloxicam
- metformin
- naproxen
- omeprazole
- pantoprazole
- prednisone
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Tylenol PM (acetaminophen / diphenhydramine)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
Aleve PM alcohol/food interactions
There are 4 alcohol/food interactions with Aleve PM (diphenhydramine / naproxen).
Aleve PM disease interactions
There are 19 disease interactions with Aleve PM (diphenhydramine / naproxen) which include:
- depression
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
- sodium
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
Report options
More about Aleve PM (diphenhydramine / naproxen)
- Aleve PM consumer information
- Compare alternatives
- Reviews (42)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: analgesic combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Tramadol
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Cyclobenzaprine
Cyclobenzaprine is a muscle relaxant and works by blocking pain sensations. Includes ...
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Aspirin
Aspirin is used to treat mild to moderate pain and to reduce fever or inflammation. Learn about ...
Naproxen
Naproxen is a nonsteroidal anti-inflammatory drug used to treat pain or inflammation caused by ...
Oxycodone
Oxycodone is an opioid analgesic used to treat moderate to severe pain; it has a high potential for ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
