Benadryl Allergy Interactions
There are 449 drugs known to interact with Benadryl Allergy (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 15 are major, 431 are moderate, and 3 are minor.
- View all 449 medications that may interact with Benadryl Allergy
- View Benadryl Allergy alcohol/food interactions (1)
- View Benadryl Allergy disease interactions (8)
Most frequently checked interactions
View interaction reports for Benadryl Allergy (diphenhydramine) and the medicines listed below.
- acetaminophen
- albuterol
- amlodipine
- aspirin
- atorvastatin
- clonazepam
- cyclobenzaprine
- famotidine
- gabapentin
- hydroxyzine
- ibuprofen
- levothyroxine
- lisinopril
- loratadine
- losartan
- magnesium oxide
- melatonin
- meloxicam
- metformin
- omeprazole
- ondansetron
- pantoprazole
- prednisone
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
Benadryl Allergy alcohol/food interactions
There is 1 alcohol/food interaction with Benadryl Allergy (diphenhydramine).
Benadryl Allergy disease interactions
There are 8 disease interactions with Benadryl Allergy (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
More about Benadryl Allergy (diphenhydramine)
- Benadryl Allergy consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (30)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
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Montelukast
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Xolair
Xolair injection (omalizumab) is used to reduce the risk of severe food allergy reactions ...
Fluticasone nasal
Fluticasone nasal is used for allergic rhinitis, allergies, chronic rhinosinusitis with nasal ...
Hydroxyzine
Hydroxyzine is an antihistamine used to treat itching, hives, and anxiety. It also acts as a ...
Ondansetron
Ondansetron is used to prevent nausea and vomiting caused by surgery, chemotherapy, or radiation by ...
Cetirizine
Cetirizine treats cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose ...
Zofran
Zofran (ondansetron) is used to prevent nausea and vomiting caused by surgery or cancer medicines ...
Triamcinolone nasal
Triamcinolone nasal is used for allergic rhinitis, allergies
Methylprednisolone
Methylprednisolone is used to treat conditions such as allergies, arthritis, lupus and ulcerative ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.