Simbrinza Drug Interactions
Currently displaying a list of 378 drugs known to interact with Simbrinza (brimonidine / brinzolamide ophthalmic).
- 8 major drug interactions
- 370 moderate drug interactions
Medications known to interact with Simbrinza
Note: Showing generic names only.
A
- acebutolol
- acetazolamide
- acetylcarbromal
- acrivastine
- alfentanil
- alfuzosin
- alprazolam
- alprostadil
- amantadine
- ambrisentan
- amiloride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amyl nitrite
- apomorphine
- aprocitentan
- aripiprazole
- asenapine
- aspirin
- atenolol
- avanafil
- azatadine
- azelastine nasal
- azilsartan medoxomil
B
- baclofen
- benazepril
- bendroflumethiazide
- benzthiazide
- benztropine
- bepridil
- betaxolol
- betaxolol ophthalmic
- biperiden
- bismuth subsalicylate
- bisoprolol
- bosentan
- brexanolone
- brexpiprazole
- brivaracetam
- bromocriptine
- brompheniramine
- bumetanide
- buprenorphine
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- candesartan
- cannabidiol
- cannabis
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carteolol
- carteolol ophthalmic
- carvedilol
- cenobamate
- cetirizine
- chlophedianol
- chloral hydrate
- chlorcyclizine
- chlordiazepoxide
- chlormezanone
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorthalidone
- chlorzoxazone
- choline salicylate
- citalopram
- clemastine
- clevidipine
- clobazam
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- codeine
- cyclandelate
- cyclizine
- cyclobenzaprine
- cyproheptadine
D
- dantrolene
- daridorexant
- deserpidine
- desipramine
- dexbrompheniramine
- dexchlorpheniramine
- dexmedetomidine
- dextromethorphan
- dezocine
- diazepam
- diazoxide
- dichlorphenamide
- difelikefalin
- diflunisal
- digitoxin
- digoxin
- diltiazem
- dimenhydrinate
- diphenhydramine
- divalproex sodium
- doxazosin
- doxepin
- doxepin topical
- doxylamine
- dronabinol
- droperidol
- duloxetine
E
- enalapril
- enalaprilat
- entacapone
- eplerenone
- epoprostenol
- eprosartan
- escitalopram
- esketamine
- esmolol
- estazolam
- eszopiclone
- ethacrynic acid
- ethanol
- ethaverine
- ethchlorvynol
- ethosuximide
- ethotoin
- ezogabine
F
- felbamate
- felodipine
- fenoldopam
- fentanyl
- flavoxate
- flibanserin
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosinopril
- fosphenytoin
- fospropofol
- furazolidone
- furosemide
G
H
- halazepam
- haloperidol
- heroin
- hydralazine
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxyzine
I
- iloperidone
- iloprost
- imipramine
- indapamide
- irbesartan
- isocarboxazid
- isosorbide
- isosorbide dinitrate
- isosorbide mononitrate
- isoxsuprine
- isradipine
K
L
- labetalol
- lamotrigine
- landiolol
- lemborexant
- levamlodipine
- levetiracetam
- levobetaxolol ophthalmic
- levobunolol ophthalmic
- levocetirizine
- levodopa
- levomethadyl acetate
- levorphanol
- linezolid
- lisinopril
- lithium
- lofexidine
- loperamide
- lorazepam
- losartan
- loxapine
- lumateperone
- lurasidone
M
- magnesium salicylate
- maprotiline
- mecamylamine
- meclizine
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methazolamide
- methdilazine
- methocarbamol
- methotrimeprazine
- methsuximide
- methyclothiazide
- methyldopa
- methylene blue
- metipranolol ophthalmic
- metoclopramide
- metolazone
- metoprolol
- mibefradil
- midazolam
- minoxidil
- mirtazapine
- moexipril
- molindone
- morphine
- morphine liposomal
N
- nabilone
- nadolol
- nalbuphine
- nebivolol
- nefazodone
- nesiritide
- nicardipine
- nifedipine
- nimodipine
- nisoldipine
- nitroglycerin
- nitroprusside
- nortriptyline
O
- olanzapine
- oliceridine
- olmesartan
- olopatadine nasal
- opicapone
- opium
- orphenadrine
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
- ozanimod
P
- paliperidone
- papaverine
- paraldehyde
- paramethadione
- paroxetine
- penbutolol
- pentazocine
- pentobarbital
- perampanel
- pergolide
- perindopril
- perphenazine
- phenacemide
- phencyclidine
- phenelzine
- phenindamine
- phenobarbital
- phensuximide
- phentolamine
- phenytoin
- pimozide
- pindolol
- polythiazide
- pramipexole
- prazosin
- pregabalin
- primidone
- procarbazine
- prochlorperazine
- procyclidine
- promazine
- promethazine
- propiomazine
- propofol
- propoxyphene
- propranolol
- protriptyline
- pyrilamine
Q
R
- ramelteon
- ramipril
- rasagiline
- rauwolfia serpentina
- remifentanil
- remimazolam
- reserpine
- risperidone
- ropinirole
- rotigotine
- rufinamide
S
- safinamide
- salsalate
- scopolamine
- secobarbital
- selegiline
- selexipag
- sertraline
- sibutramine
- sildenafil
- silodosin
- sodium oxybate
- sodium salicylate
- sodium thiosalicylate
- sotalol
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- sufentanil
- suvorexant
T
- tadalafil
- tamsulosin
- tapentadol
- tasimelteon
- telmisartan
- temazepam
- terazosin
- tetrabenazine
- thalidomide
- thiethylperazine
- thiopental
- thioridazine
- thiothixene
- tiagabine
- timolol
- timolol ophthalmic
- tizanidine
- tolcapone
- topiramate
- torsemide
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- treprostinil
- triamterene
- triazolam
- trichlormethiazide
- trifluoperazine
- triflupromazine
- trihexyphenidyl
- trimeprazine
- trimethadione
- trimethaphan camsylate
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
V
Z
Simbrinza alcohol/food interactions
There is 1 alcohol/food interaction with Simbrinza (brimonidine / brinzolamide ophthalmic).
Simbrinza disease interactions
There are 10 disease interactions with Simbrinza (brimonidine / brinzolamide ophthalmic) which include:
- hematologic toxicity
- hypersensitivity reactions
- porphyria
- cardiovascular
- depression
- renal/liver
- crystalluria
- liver disease
- renal dysfunction
- urinary obstruction
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More about Simbrinza (brimonidine / brinzolamide ophthalmic)
- Simbrinza consumer information
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (28)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: ophthalmic glaucoma agents
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.