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Angiotensin Converting Enzyme Inhibitors

Other names: ACE inhibitors

What are Angiotensin Converting Enzyme Inhibitors

ACE inhibitors (angiotensin-converting enzyme inhibitors) are a group of medicines used to treat high blood pressure (hypertension), heart failure, or to reduce complications of heart attack (myocardial infarction). They can also be used to help slow kidney disease progression in diabetic patients or patients with chronic kidney disease.

How they work

ACE inhibitors action is to reduce the amount of angiotensin II produced. Usually angiotensin II has an effect on the body to increase blood pressure, increase blood volume and increase pressure in the kidney. As the ACE inhibitor lowers the amount of angiotensin II, this causes the blood vessels to become wider and there is an increase in the amount of urine produced by the kidneys. The result of this is the blood pressure goes down, blood volume decreases and there is a reduction of pressure in the kidney.

The lowering of angiotensin II levels by ACE inhibitors also causes a drop in noradrenalin and aldosterone levels, which helps to reduce blood pressure. Another effect ACE inhibitors have is to increase bradykinin which also causes the blood vessels to widen with a further decrease in blood pressure.

What they treat

ACE inhibitors are used to treat

  • high blood pressure (hypertension)
  • heart failure
  • reduce complications of heart attack
  • help protect kidney function.

Side effects

ACE inhibitors may cause some side effects which can depend on which type of ACE inhibitors is taken. Side effects may include low blood pressure (hypotension), dry cough, high potassium levels (hyperkalemia), dizziness, reduced kidney function, swelling of the face or airways (angioedema).

List of Angiotensin Converting Enzyme Inhibitors:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
captopril systemic (Pro, More...)
5 reviews
fosinopril systemic (Pro, More...)
2 reviews
moexipril systemic (Pro, More...)
2 reviews
quinapril systemic (Pro, More...)
7 reviews
ramipril systemic (Pro, More...)
62 reviews
enalapril systemic (Pro, More...)
15 reviews
trandolapril systemic (Pro, More...)
1 review
benazepril systemic (Pro, More...)
14 reviews
perindopril systemic (Pro, More...)
10 reviews
lisinopril systemic (Pro, More...)
449 reviews
enalaprilat systemic (Pro, More...)
0 reviewsAdd rating