Vibegron Dosage

Medically reviewed by Drugs.com. Last updated on Mar 26, 2025.

Usual Adult Dose for Overactive Bladder Syndrome

75 mg orally once a day

Use: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults, including adult males on pharmacological therapy for benign prostatic hyperplasia

Renal Dose Adjustments

Mild, moderate, or severe renal dysfunction (estimated GFR 15 to less than 90 mL/min/1.73 m2): No adjustment recommended
Estimated GFR less than 15 mL/min/1.73 m2 (without hemodialysis): Not recommended

Comments:

• This drug has not been studied in patients with estimated GFR less than 15 mL/min/1.73 m2 (with or without hemodialysis).

Liver Dose Adjustments

Mild to moderate liver dysfunction (Child-Pugh A and B): No adjustment recommended
Severe liver dysfunction (Child-Pugh C): Not recommended

Comments:

• This drug has not been studied in patients with severe liver dysfunction.

Precautions

CONTRAINDICATIONS:

• Known hypersensitivity to the active component or any of the ingredients

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Estimated GFR less than 15 mL/min/1.73 m2 (with hemodialysis): Not recommended

Comments:

• This drug has not been studied in patients with estimated GFR less than 15 mL/min/1.73 m2 (with or without hemodialysis).

Other Comments

Administration advice:

• Administer with or without food.
• Swallow tablets whole with a glass of water.
• Tablets may also be crushed, mixed with a tablespoon (about 15 mL) of applesauce, and administered immediately with a glass of water.

Storage requirements:

• Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).

General:

• Hypersensitivity reactions (e.g., angioedema) have occurred.

Monitoring:

• Genitourinary: For signs/symptoms of urinary retention

Patient advice:

• Read the US FDA-approved patient labeling (Patient Information).
• Contact your health care provider if symptoms consistent with urinary retention develop during therapy.
• Discontinue this drug and seek medical attention immediately if angioedema associated with upper airway swelling occurs.

Frequently asked questions

• How long does it take for Gemtesa (vibegron) to work?
• How does Gemtesa (vibegron) work?
• Does Gemtesa (vibegron) cause weight gain?
• Gemtesa Coupon: Do I qualify and how much can I save?

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer