Medically reviewed by Drugs.com. Last updated on Sep 28, 2021.
Applies to the following strengths: 200 mg
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Skin and Structure Infection
200 mg IV or orally once a day for 6 days
Use: For the treatment of acute bacterial skin and skin structure infections due to susceptible isolates of Staphylococcus aureus (including methicillin-resistant and methicillin-susceptible isolates), Streptococcus pyogenes, S agalactiae, S anginosus group (including S anginosus, S intermedius, and S constellatus), Enterococcus faecalis
Usual Pediatric Dose for Skin and Structure Infection
12 years or older: 200 mg IV or orally once a day for 6 days
Use: For the treatment of acute bacterial skin and skin structure infections due to susceptible isolates of S aureus (including methicillin-resistant and methicillin-susceptible isolates), S pyogenes, S agalactiae, S anginosus group (including S anginosus, S intermedius, and S constellatus), E faecalis
Renal Dose Adjustments
No adjustment recommended.
Liver Dose Adjustments
No adjustment recommended.
Safety and efficacy have not been established in patients younger than 12 years.
Consult WARNINGS section for additional precautions.
Hemodialysis: No adjustment recommended.
Peritoneal dialysis: Data not available
- IV: Administer via IV infusion over 1 hour; do not administer as IV push or bolus. This drug is not for intra-arterial, IM, intrathecal, intraperitoneal, or subcutaneous administration.
- IV: Do not mix with other agents during administration; if the same IV line is used for sequential infusion of several drugs, flush the line with a compatible infusion solution before and after infusion of this drug.
- Do not adjust dose when switching from IV to oral administration (no adjustments needed).
- Oral: Administer with or without food; no dietary restrictions.
- Consult the manufacturer product information regarding missed doses.
- IV: Total time from reconstitution to administration should not exceed 24 hours at room temperature or refrigerated at 2C to 8C (36F to 46F); discard unused portion.
- IV formulation: Must be reconstituted and then diluted; the manufacturer product information should be consulted.
- Compatible diluents and IV solutions: Sterile Water for Injection; 0.9% Sodium Chloride Injection, USP
- Incompatible: Any solution containing divalent cations (e.g., calcium, magnesium), including Lactated Ringers Injection and Hartmann's Solution
- Limited data available on compatibility of this drug with other IV substances, additives, or other drugs; they should not be added to tedizolid single-dose vials or infused simultaneously.
- To reduce the development of drug-resistant organisms and maintain effective therapy, this drug should be used only to treat infections proven or strongly suspected to be caused by susceptible bacteria.
- Culture and susceptibility information should be considered when selecting/modifying antibacterial therapy or, if no data are available, local epidemiology and susceptibility patterns may be considered when selecting empiric therapy.
- Read the US FDA-approved patient labeling (Patient Information).
- Avoid missing doses and complete the entire course of therapy.
- Consult physician at once if watery and bloody stools (with or without stomach cramps and fever) develop.
- Patients of childbearing potential: Notify healthcare provider of known/suspected pregnancy.
More about tedizolid
- Side effects
- Drug interactions
- During pregnancy or Breastfeeding
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- Drug class: oxazolidinone antibiotics
- Drug Information
- Tedizolid (Advanced Reading)
- Tedizolid Intravenous (Advanced Reading)
- Tedizolid Tablets
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